D
David M. Jacobowitz
Researcher at National Institutes of Health
Publications - 389
Citations - 26961
David M. Jacobowitz is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Calretinin & Hypothalamus. The author has an hindex of 84, co-authored 389 publications receiving 26673 citations. Previous affiliations of David M. Jacobowitz include Uniformed Services University of the Health Sciences & Hebrew University of Jerusalem.
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Journal ArticleDOI
Secretin in the Rat Hypothalamo-Pituitary System: Localization, Identification and Characterization
Clivel G. Charlton,Clivel G. Charlton,Thomas L. O'Donohue,Thomas L. O'Donohue,Russell L. Miller,David M. Jacobowitz +5 more
TL;DR: It appears that there may be a secretinergic pathway between the brain and the neurointermediate lobe of the pituitary of the rat, with a relatively high concentration of SLI reported to occur in the hypothalamus.
Journal ArticleDOI
Biochemical mapping of noradrenergic projections of axons in the dorsal noradrenergic bundle.
TL;DR: The recent combination of microdissection techniques with sensitive radioisotopic assays has augmented whole brain biochemical measurements 1,3,18,29, microelectrode recording 4, autoradiography 30 and histofluorescence techniques 2,~,7-11, 14,z0,22,23,25,26,31 in detailed mapping of the projections and pathways ofnoradrenergic neurons in the central nervous system.
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Effects of food restriction on the periodicity of corticosteroids in plasma and on monoamine concentrations in discrete brain nuclei
Dorothy T. Krieger,Dorothy T. Krieger,Dorothy T. Krieger,William R. Crowley,William R. Crowley,William R. Crowley,Thomas L. O'Donohue,Thomas L. O'Donohue,Thomas L. O'Donohue,David M. Jacobowitz,David M. Jacobowitz,David M. Jacobowitz +11 more
TL;DR: The results indicate that the shift in theperiodicity of corticosteroid secretion produced by a restricted feeding regime is accompanied by changes in the periodicity of neurotransmitter concentrations in specific regions of the brain, and that such patterns are dissimilar in different regions.
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Localization of substance P mRNA in cholinergic cells of the rat laterodorsal tegmental nucleus:In situ hybridization histochemistry and immunocytochemistry
TL;DR: In situ hybridization histochemical techniques in combination with immunocytochemistry and acetylcholinesterase (AChE) histochemistry were used to study the colocalization of messenger RNA (mRNA) encoding the neuropeptide substance P in cholinergic cells of the laterodorsal tegmental nucleus (LDT) of the rat pontine brain stem.
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Corticosterone effects on rat calretinin mRNA in discrete brain nuclei and the testes
TL;DR: It is suggested that corticosterone's effects on brain calretinin may be due to its pathological effects, e.g. energy depletion of brain cells or interference with the normal support functions of glia.