D
David S.P. Tan
Researcher at National University of Singapore
Publications - 123
Citations - 6151
David S.P. Tan is an academic researcher from National University of Singapore. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 31, co-authored 89 publications receiving 4817 citations. Previous affiliations of David S.P. Tan include Princess Margaret Cancer Centre & Institute of Cancer Research.
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Journal ArticleDOI
ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease
Nicoletta Colombo,Cristiana Sessa,A. du Bois,Jonathan A. Ledermann,WG McCluggage,Iain A. McNeish,P. Morice,Sandro Pignata,Isabelle Ray-Coquard,Ignace Vergote,Thaïs Baert,I. Belaroussi,A. Dashora,Siel Olbrecht,François Planchamp,Denis Querleu,Susana Banerjee,P. Blecharz,Ilan Bruchim,David Cibula,Nicole Concin,Ben Davidson,Mojgan Devouassoux-Shisheboran,Annamaria Ferrero,R.M. Glasspool,Antonio González-Martín,Viola Heinzelmann-Schwarz,Florence Joly,J. W. Kim,Frédéric Kridelka,Domenica Lorusso,Sven Mahner,Mikio Mikami,Mansoor Raza Mirza,Shibani Nicum,Dearbhaile M. O'Donnell,Patricia Pautier,Alexandros Rodolakis,Jalid Sehouli,Fatih Selcukbiricik,Naveena Singh,David S.P. Tan,Dirk Timmerman,Germana Tognon,J. van der Velden,Petronella O. Witteveen,AG Zeimet +46 more
TL;DR: The recommendations presented here are based on the best available evidence and expert agreement and are presented with a summary of evidence supporting each recommendation.
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"BRCAness" Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated With BRCA1 and BRCA2 Mutations
David S.P. Tan,Christian Rothermundt,Karen Thomas,Elizabeth Bancroft,Rosalind A. Eeles,Susan Shanley,Audrey Ardern-Jones,Andrew R. Norman,Stanley B. Kaye,Martin Gore +9 more
TL;DR: There exists a clinical syndrome of BRCAness that includes serous histology, high response rates to first and subsequent lines of platinum-based treatment, longer TFIs between relapses, and improved OS.
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Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research
TL;DR: Recent advances in the understanding of malignant ascites pathophysiology, the development of new methods to characterize its molecular features and how these findings can be used to improve the treatment ofmalignant ascite, particularly in the context of ovarian cancer are discussed.
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Mechanisms of transcoelomic metastasis in ovarian cancer
TL;DR: Future high throughput microarray studies that compare changes at a genomic and gene expression level between primary ovarian tumours and their peritoneal metastases are hoped to lead to a more conclusive picture of transcoelomic metastasis, and to delineate the key molecular players in this process.
Journal ArticleDOI
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
Britta Weigelt,Alan Mackay,Roger A'Hern,Rachael Natrajan,David S.P. Tan,Mitch Dowsett,Mitch Dowsett,Alan Ashworth,Jorge S. Reis-Filho +8 more
TL;DR: Although every SSP identifies molecular subtypes with similar survival, they do not reliably assign the same patients to the same molecular subtype, so stringent standardisation of methodologies and definitions for identification of breast cancer molecular sub types is needed.