D
Dearbhaile M. O'Donnell
Researcher at Trinity College, Dublin
Publications - 48
Citations - 2820
Dearbhaile M. O'Donnell is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Cancer & Dendritic cell. The author has an hindex of 21, co-authored 44 publications receiving 1633 citations. Previous affiliations of Dearbhaile M. O'Donnell include St James's University Hospital.
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ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease
Nicoletta Colombo,Cristiana Sessa,A. du Bois,Jonathan A. Ledermann,WG McCluggage,Iain A. McNeish,P. Morice,Sandro Pignata,Isabelle Ray-Coquard,Ignace Vergote,Thaïs Baert,I. Belaroussi,A. Dashora,Siel Olbrecht,François Planchamp,Denis Querleu,Susana Banerjee,P. Blecharz,Ilan Bruchim,David Cibula,Nicole Concin,Ben Davidson,Mojgan Devouassoux-Shisheboran,Annamaria Ferrero,R.M. Glasspool,Antonio González-Martín,Viola Heinzelmann-Schwarz,Florence Joly,J. W. Kim,Frédéric Kridelka,Domenica Lorusso,Sven Mahner,Mikio Mikami,Mansoor Raza Mirza,Shibani Nicum,Dearbhaile M. O'Donnell,Patricia Pautier,Alexandros Rodolakis,Jalid Sehouli,Fatih Selcukbiricik,Naveena Singh,David S.P. Tan,Dirk Timmerman,Germana Tognon,J. van der Velden,Petronella O. Witteveen,AG Zeimet +46 more
TL;DR: The recommendations presented here are based on the best available evidence and expert agreement and are presented with a summary of evidence supporting each recommendation.
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ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma.
Nicole Concin,Xavier Matias-Guiu,Ignace Vergote,David Cibula,Mansoor Raza Mirza,Simone Marnitz,Jonathan A. Ledermann,Tjalling Bosse,Cyrus Chargari,Anna Fagotti,Christina Fotopoulou,Antonio Gonzalez Martin,Sigurd Lax,Domenica Lorusso,Christian Marth,Philippe Morice,Remi A. Nout,Dearbhaile M. O'Donnell,Denis Querleu,Maria Rosaria Raspollini,Jalid Sehouli,Alina Sturdza,Alexandra Taylor,Anneke M. Westermann,Pauline Wimberger,Nicoletta Colombo,François Planchamp,Carien L. Creutzberg +27 more
TL;DR: A European consensus conference on endometrial carcinoma was held in 2014 to produce multi-disciplinary evidence-based guidelines on selected questions as mentioned in this paper, and the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy and Oncologies (ESTRO), and the EPSP jointly decided to update these evidence-base guidelines and to cover new topics in order to improve the quality of care for women with endometrium carcinoma across Europe and worldwide.
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The role of inflammation in the pathogenesis of non-small cell lung cancer.
TL;DR: A review of recent insights gained in the understanding of the role played by chronic inflammation in lung carcinogenesis is provided in this paper, where the usefulness of quantification of different populations of lymphocytes, natural killer cells, macrophages, and mast cells within the tumor microenvironment in non-small cell lung cancer is discussed.
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Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal carcinoma treatment (ICON8): primary progression free survival analysis results from a GCIG phase 3 randomised controlled trial
Andrew R Clamp,Elizabeth C. James,Iain A. McNeish,Andrew Dean,Jae Weon Kim,Dearbhaile M. O'Donnell,Jane Hook,Christopher Coyle,Sarah P. Blagden,James D. Brenton,Raj Naik,Timothy J. Perren,Sudha Sundar,Adrian Cook,Gosala S. Gopalakrishnan,Hani Gabra,Hani Gabra,Rosemary Lord,Graham Dark,Helena M. Earl,Marcia Hall,Susana Banerjee,Rosalind Glasspool,Rachel Jones,Sarah Williams,Ann Marie Swart,S. P. Stenning,Mahesh K. B. Parmar,Richard Kaplan,Jonathan A. Ledermann +29 more
TL;DR: Weekly dose-dense chemotherapy can be delivered successfully as first-line treatment for epithelial ovarian cancer but does not significantly improve progression-free survival compared with standard 3-weekly chemotherapy in predominantly European populations.
Journal ArticleDOI
Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naive T-cell priming.
Alison Merrick,Fiona Errington,K Milward,Dearbhaile M. O'Donnell,Kevin J. Harrington,Andrew Bateman,Hardev Pandha,Richard G. Vile,Ewan E. Morrison,Peter Selby,Alan Melcher +10 more
TL;DR: Irradiation of DC in vitro, and potentially in vivo, has a significant impact on their function, and may shift the balance between T-cell activation and tolerisation in DC-mediated immune responses.