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David Vrbata
Researcher at Charles University in Prague
Publications - 6
Citations - 52
David Vrbata is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Micelle & Phenylboronic acid. The author has an hindex of 4, co-authored 5 publications receiving 34 citations.
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Journal ArticleDOI
Preparation of lactic acid- and glucose-responsive poly(ε-caprolactone)-b-poly(ethylene oxide) block copolymer micelles using phenylboronic ester as a sensitive block linkage
David Vrbata,Mariusz Uchman +1 more
TL;DR: This novel block copolymer may contribute to the field of selective, lactic acid- and/or glucose-responsive drug delivery vehicle design under both pathological and physiological conditions.
Journal ArticleDOI
Novel conjugated polyelectrolytes based on polythiophene bearing phosphonium side groups
TL;DR: The synthesis and photophysical properties of poly{3]-6-(triethylphosphonium)hexyl]-thiophene-2,5-diyl bromide and poly{ 3]-triphenylphosphonic hexonium)-hexyl-thiophenyl]-THiophene 2,5 -diylbromide are reported in this article.
Journal ArticleDOI
Preparation of membrane-mimicking lamellar structures by molecular confinement of hybrid nanocomposites.
David Vrbata,Vladimír Ďorďovič,Jani Seitsonen,Janne Ruokolainen,Olga Janoušková,Mariusz Uchman,Pavel Matějíček +6 more
TL;DR: Telechelic PEO with glucose molecules are prepared to form water-soluble lamellar nanostructures by co-assembly with metallacarborane to serve as delivery agents for boron clusters and benzoxaboroles.
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Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3.
David Vrbata,Marcela Filipová,Marina Rodrigues Tavares,Jakub ervený,M. Vlachová,Milada Šírová,Helena Pelantová,Lucie Petrásková,Ladislav Bumba,Rafał Konefał,Tomáš Etrych,Vladimir Kren,Petr Chytil,Pavla Bojarová +13 more
TL;DR: A library of C-3 aryl-substituted thiodigalactoside inhibitors and their multivalent N-(2-hydroxypropyl)methacrylamide (HPMA)-based counterparts with two different glycomimetic contents are synthesized and appear to be prospective modulators of the tumor microenvironment applicable in the therapy of Gal-3-associated cancers.
Journal ArticleDOI
Synthesis and characterization of metallo-supramolecular polymers from thiophene-based unimers bearing pybox ligands
Sviatoslav Hladysh,Daniela Václavková,David Vrbata,Dmitrij Bondarev,Dmitrij Bondarev,David Havlíček,Jan Svoboda,Jiří Zedník,Jiří Vohlídal +8 more
TL;DR: A series of novel metallo-supramolecular polymers was successfully prepared, based on 2,6-bis(2-oxazolinyl)pyridine building blocks consisting of pyridine flanked by two oxazoline rings as a tridentate binding site bridged with thiophene, bithiophene and thienothiophene as a linker as discussed by the authors.