Dawei Yang

TL;DR: The assay with [U-13C3]acetone allows measuring the 2H-enrichment of water even in biological samples containing acetone, which is more rapid and economical than the classical isotope ratio mass spectrometric assay of the enrichment of hydrogen gas derived from the reduction of water.

TL;DR: In this article, the conditions of validity of mass isotopomer distribution analysis of glucose labeled from 15N, 13C-, or 2H-labeled monomeric units were tested in perfused rat livers, live rats, and live monkeys.

TL;DR: Isotope dilution gas chromatographic mass spectrometric assays were developed for the concentration of shortchain fatty acids and of lactate in plasma and can be used to study carbohydrate fermentation in humans, ruminants and non-ruminant mammals.

TL;DR: Fractional hepatic lipogenesis measured in vivo by MIDA may be underestimated because of the assumption of constant enrichment of lipogenic acetyl-CoA in all hepatocytes, according to which the threefold decrease in acetate concentration and the sevenfold decreaseIn acetate enrichment across the liver strongly suggest that the enrichment oflipogenic acetate decreases across the Liver.

TL;DR: Calculating gluconeogenesis's contributions to glucose production and Cori cycling from mass isotopomer distributions in blood glucose and lactate during [U-13C6]glucose infusion and corrected equations are introduced and applied to data from subjects fasted for 12 and 60 h.