Dean E. Carter

TL;DR: Data demonstrate that MMA(III), an intermediate in in organic arsenic methylation, is highly toxic and again raises the question as to whether methylation of inorganic arsenic is a detoxication process.

TL;DR: The solution reactions between GSH and arsenate, arsenite, and their methylated metabolites, monomethylarsonic acid (MMA and dimethylarsinic acid (DMA), were characterized using 1H and 13C NMR under a nitrogen atmosphere to result from direct reactions between the two compounds.

TL;DR: Members Mario Altamirano-Lozano, Unidad de Investigación en Genética y Toxicología Ambiental (UNIGEN), Facultad de Estudios Superiores-Zaragoza, Battalla del 5 de mayo esq.

TL;DR: There is insufficient evidence to equate the different arsenic compounds, and there are several differences in the toxicity of the arsenic compounds that will require substantial research.

TL;DR: The rapid elimination of parent compound was due mainly to biotransformation since less that 2% of the dose was excreted unchanged in the urine and bile, and the metabolism of acrylamide appears to be mediated through glutathione conjugation in the liver since the major urinary metabolite was N-acetyl-S-(3-amino-3-oxypropyl)cysteine.