Showing papers by "Dedy Darnaedi published in 2004"
TL;DR: Three new stilbene oligomers were isolated from the stem bark of Vatica pauciflora and elucidated by means of spectroscopic data interpretation, especially HMBC and NOESY NMR experiments.
Abstract: Three new stilbene oligomers (1-3) were isolated from the stem bark of Vatica pauciflora. The structures of a resveratrol heptamer (pauciflorol D) (1), a resveratrol dimer (pauciflorol E) (2), and an indanone derivative (pauciflorol F) (3) were elucidated by means of spectroscopic data interpretation, especially HMBC and NOESY NMR experiments.
132 citations
TL;DR: Two new stilbene tetramers, grandiphenols A (1) and B (2), along with ten known stilbenzene oligomers and bergenin were isolated from the stem of Dipterocarpus grandiflorus as discussed by the authors.
Abstract: Two new stilbene tetramers, grandiphenols A (1) and B (2), along with ten known stilbene oligomers and bergenin were isolated from the stem of Dipterocarpus grandiflorus. The structures of 1 and 2 composed of four resveratrol (=5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) units had eight asymmetric C-atoms in the partial structures of a tetrahydrofuran and two dihydrobenzofuran moieties. Detailed spectroscopic analyses, especially HMBC and NOESY experiments, allowed to differentiate the configurations of 1 and 2.
29 citations
TL;DR: Eryvarin R (6) is an unusual 3‐aryl‐2,3‐dihydrobenzofuran derivative with a formyl (CHO) group that showed potent antibacterial activity against methicillin‐resistant Staphylococcus aureus.
Abstract: Three new isoflavonoids, eryvarins M-O (1-3), two new 2-arylbenzofurans, eryvarins P and Q (4 and 5), and a new 3-aryl-2,3-dihydrobenzofuran, eryvarin R (6), together with three known compounds, were isolated from the roots of Erythrina variegata. The structures of these compounds were established by spectroscopic analysis. Eryvarin R (6) is an unusual 3-aryl-2,3-dihydrobenzofuran derivative with a formyl (CHO) group. Eryvarin Q (5) showed potent antibacterial activity against methicillin-resistant Staphylococcus aureus.
26 citations
TL;DR: In this paper, a resveratrol hexamer, upunaphenol A, was isolated from an acetone soluble part of stem of Upuna borneensis (Dipterocarpaceae).
Abstract: A new resveratrol hexamer, upunaphenol A, was isolated from an acetone soluble part of stem of Upuna borneensis (Dipterocarpaceae). The structure, which has twelve asymmetric carbon atoms on the partial structures of a dibenzobicyclo[3.2.1]octadiene ring and four dihydrobenzofuran rings, was determined by spectral analysis including 1D and 2D NMR spectral experiments. Resveratrol and four known resveratrol oligomers, ampelopsin F, isoampelopsin F, vaticanols C and B, were also isolated. Upunaphenol A was found to suppress cell growth in HL60 cells through induction of apoptosis with IC 5 0 at 9.2 μM.
22 citations
TL;DR: Three acetophenone C-glycosides, 2,4,6-trihydroxyacetophenone 3-C-beta-(2'-O-p-hydroxybenzoyl)-glucopyranoside, and two resveratrol O- Glycosides together with three known compounds were isolated from the acetone soluble part of stem of Upuna borneensis (Dipterocarpaceae).
15 citations
TL;DR: In this article, the MeOH extract of the leaves of Chisocheton weinlandii Harms (Meliaceae) revealed two new open-chain spermidine alkaloids.
Abstract: The investigation of the MeOH extract of the leaves of Chisocheton weinlandii Harms (Meliaceae) revealed two new open-chain spermidine alkaloids, chisitine 1 (1) and chisitine 2 (2). Their structures were elucidated by NMR spectroscopy, tandem-mass spectrometry, and independant syntheses (Scheme 3). Detailed MS/MS fragmentation pathways are discussed for both compounds based on H/D exchange and 18O-labeling experiments (Schemes 1 and 2).
13 citations
TL;DR: In this article, the MeOH extract of the leaves of Chisocheton weinlandii Harms (Meliaceae) revealed two new open-chain spermidine alkaloids.
Abstract: The investigation of the MeOH extract of the leaves of Chisocheton weinlandii Harms (Meliaceae) revealed two new open-chain spermidine alkaloids, chisitine 1 (1) and chisitine 2 (2). Their structures were elucidated by NMR spectroscopy, tandem-mass spectrometry, and independant syntheses (Scheme 3). Detailed MS/MS fragmentation pathways are discussed for both compounds based on H/D exchange and 18O-labeling experiments (Schemes 1 and 2).
2 citations