D
Deeksha Sharma
Researcher at Defence Research and Development Organisation
Publications - 7
Citations - 85
Deeksha Sharma is an academic researcher from Defence Research and Development Organisation. The author has contributed to research in topics: Solid lipid nanoparticle & Granulation tissue. The author has an hindex of 3, co-authored 7 publications receiving 22 citations.
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Intranasal delivery of Naloxone-loaded solid lipid nanoparticles as a promising simple and non-invasive approach for the management of opioid overdose.
Nazeer Hasan,Nazeer Hasan,Nazeer Hasan,Mohammad Imran,Prashant Kesharwani,Kushagra Khanna,Kushagra Khanna,Ritu Karwasra,Nitin Sharma,Sonalika Rawat,Deeksha Sharma,Farhan Jalees Ahmad,Gaurav K. Jain,Aseem Bhatnagar,Sushama Talegaonkar +14 more
TL;DR: In this paper, the authors developed intranasal solid-lipid nanoparticles in which naloxone was incorporated for the higher brain disposition of Noxone with superior therapeutic effects for the reversal of toxicity of opioid overdose.
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Pomegranate supplementation attenuates inflammation, joint dysfunction via inhibition of NF-κB signaling pathway in experimental models of rheumatoid arthritis.
TL;DR: The research work represents the first report on inhibitory mechanism of NF-κB by pomegranate rind extract, enriched in tannins and flavanoids, in amelioration of adjuvant-induced arthritis.
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Novel gum acacia based macroparticles for colon delivery of Mesalazine: Development and gammascintigraphy study
Nitin Sharma,Anjana Sharma,Aseem Bhatnagar,Dhruv Kumar Nishad,Ritu Karwasra,Kushagra Khanna,Deeksha Sharma,Neeraj Kumar,Gaurav K. Jain +8 more
TL;DR: GA based enteric coated tablet may be a promising carrier for colon-specific delivery of MLZ in ulcerative colitis, confirmed in the present study.
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Enhancement in brain uptake of vitamin D3 nanoemulsion for treatment of cerebral ischemia: formulation, gamma scintigraphy and efficacy study in transient middle cerebral artery occlusion rat models
Mukesh Kumar,Mukesh Kumar,Dhruv Kumar Nishad,Anoop Kumar,Aseem Bhatnagar,Ritu Karwasra,Kushagra Khanna,S. Keerthana,Deeksha Sharma,Kamal Dua,Kamal Dua,Kamal Dua,Vijaybabu Mudaliyar,Nitin Sharma,Nitin Sharma +14 more
TL;DR: This work demonstrated better permeation, deposition, and efficacy of vitaminD3-nanoemulsion through the intranasal route of cerebral ischaemia.
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A Comparative Study of Chitosan Gel and Soframycin in the Management of Wounds
Kushagra Khanna,Deeksha Sharma,Roop K. Khar,Ritu Karwasra,Nitin Sharma,Dhruv Kumar Nishad,Aseem Bhatnagar,Harvinder Popli +7 more
TL;DR: Higher degree of deacetylation in the chitosan, GCG-3, warrants its use in the treatment and management of dermal wounds and a comparative profile with soframycin is established in experimental animals.