D
Denis Reviron
Researcher at French Institute of Health and Medical Research
Publications - 38
Citations - 2520
Denis Reviron is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: HLA-DRB1 & Population. The author has an hindex of 19, co-authored 38 publications receiving 2355 citations.
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Journal ArticleDOI
Human NK Cell Education by Inhibitory Receptors for MHC Class I
Nicolas Anfossi,Pascale Andre,Sophie Guia,Sophie Guia,Christine S. Falk,Sophie Roetynck,Sophie Roetynck,C. Andrew Stewart,C. Andrew Stewart,Violette Breso,Coralie Frassati,Denis Reviron,Derek Middleton,François Romagné,Sophie Ugolini,Sophie Ugolini,Eric Vivier +16 more
TL;DR: It is shown here that NK cells lacking inhibitory KIR for self MHC class I molecules are present in human peripheral blood, suggesting its role in the subsequent "missing self" recognition.
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Polymorphism at position −308 of the tumor necrosis factor α gene influences outcome of infliximab therapy in rheumatoid arthritis
Bénédicte Mugnier,Nathalie Balandraud,Albert Darque,Chantal Roudier,Jean Roudier,Denis Reviron +5 more
TL;DR: These data suggest that patients with a TNFalpha -308G/G genotype are better infliximab responders than are patients with A/A or A-G genotypes.
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Epstein-Barr virus load in the peripheral blood of patients with rheumatoid arthritis: accurate quantification using real-time polymerase chain reaction.
Nathalie Balandraud,Jean Baptiste Meynard,Isabelle Auger,Helene Sovran,Bénédicte Mugnier,Denis Reviron,Jean Roudier,Chantal Roudier +7 more
TL;DR: It is demonstrated that in patients with RA, the EBV DNA load in PBMCs is increased almost 10-fold compared with that in normal controls, and theEBV load is stable over time and is not obviously influenced by disease-modifying antirheumatic drugs or HLA-DR.
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HLA Association with Hematopoietic Stem Cell Transplantation Outcome: The Number of Mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 Is Strongly Associated with Overall Survival
Pascale Loiseau,Marc Busson,Marie-Lorraine Balere,A. Dormoy,Jean-Denis Bignon,Katia Gagne,L. Gebuhrer,Valérie Dubois,Isabelle Jollet,Monique Bois,Pascale Perrier,Dominique Masson,Agnès Moine,L. Absi,Denis Reviron,Virginia Lepage,Ryad Tamouza,Antoine Toubert,Evelyne Marry,Zina Chir,Jean-Pierre Jouet,Didier Blaise,Dominique Charron,Colette Raffoux +23 more
TL;DR: negative effects of HLA mismatching for either HLA-A, -B, -C, -DRB1, or -DQB1 loci on survival are demonstrated, and "Missing killer cell immunoglobulin-like receptor (KIR) ligand" evaluated on the presence of Hla-C2, and Bw4 groups in the recipients was not associated with aGVHD, survival, and relapse in this cohort of non-T cell-depleted HS
Journal ArticleDOI
Influence of shared epitope–negative HLA–DRB1 alleles on genetic susceptibility to rheumatoid arthritis
Denis Reviron,Aleth Perdriger,Eric Toussirot,Daniel Wendling,Nathalie Balandraud,Sandrine Guis,Gilbert Semana,Pierre Tiberghien,Pierre Mercier,Jean Roudier +9 more
TL;DR: The DRB1*X allele polymorphism influences susceptibility to RA, and HLA-DRB1 alleles that have a neutral or negative electric charge in their P4 pocket (DRB 1*XP4n) protect against RA.