D
Denise R. Cooper
Researcher at University of South Florida
Publications - 111
Citations - 6370
Denise R. Cooper is an academic researcher from University of South Florida. The author has contributed to research in topics: Protein kinase C & Insulin. The author has an hindex of 39, co-authored 110 publications receiving 6076 citations. Previous affiliations of Denise R. Cooper include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Adult bone marrow stromal cells differentiate into neural cells in vitro.
Juan Sanchez-Ramos,Shijie Song,Fernando Cardozo-Pelaez,C. Hazzi,Todd Stedeford,Alison E. Willing,Thomas B. Freeman,Samuel Saporta,William J. Janssen,Niketa A. Patel,Denise R. Cooper,Paul R. Sanberg +11 more
TL;DR: It is demonstrated that human and mouse BMSC can be induced to differentiate into neural cells under experimental cell culture conditions.
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Hypoxia-associated induction of early growth response-1 gene expression.
Shi Fang Yan,Jiesheng Lu,Yu Shan Zou,Jae Soh-Won,David M. Cohen,Peter M. Buttrick,Denise R. Cooper,Susan F. Steinberg,Nigel Mackman,David J. Pinsky,David M. Stern +10 more
TL;DR: It is proposed that activation of Egr-1 in response to hypoxia induces a different facet of the adaptive response than HIF-1, one component of which causes expression of tissue factor, resulting in fibrin deposition.
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Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-α and PPAR expression
Mie Okumura,Mayumi Yamamoto,Hiroya Sakuma,Toshihiro Kojima,Takako Maruyama,Marjan Jamali,Denise R. Cooper,Keigo Yasuda +7 more
TL;DR: Results suggested that hyperglycemia and hyperleptinemia increase breast cancer cell proliferation through accelerated cell cycle progression with up-regulation of cdk2 and cyclin D1 levels, which suggests the involvement of PKC-alpha, PPARalpha, and PPARgamma.
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Insulin Rapidly Increases Diacylglycerol by Activating De Novo Phosphatidic Acid Synthesis
Robert V. Farese,Thomas Suman Konda,John S. Davis,Mary L. Standaert,R J Pollet,Denise R. Cooper +5 more
TL;DR: Both phospholipid effects of insulin seem important for generating diacylglycerol and other phospholipsid-derived intracellular signaling substances.
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Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes.
TL;DR: Early insulin-induced increases in membrane and cytosolic protein kinase C activity may be related to increased diacylglycerol generation from de novo phosphatidic acid synthesis, as there were rapid increases in [3H] Glycerol incorporation into diacyLglycerols at later, as well as very early time points.