D
Denitsa Docheva
Researcher at University of Regensburg
Publications - 117
Citations - 5404
Denitsa Docheva is an academic researcher from University of Regensburg. The author has contributed to research in topics: Mesenchymal stem cell & Tendon. The author has an hindex of 34, co-authored 103 publications receiving 4271 citations. Previous affiliations of Denitsa Docheva include University Hospital Regensburg & Max Planck Society.
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Biologics for tendon repair.
TL;DR: This review describes and critically assess the current strategies for enhancing tendon repair by biological means, mainly of applying growth factors, stem cells, natural biomaterials and genes, alone or in combination, to the site of tendon damage.
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Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
Takao Sakai,Shaohua Li,Denitsa Docheva,Carsten Grashoff,Keiko Sakai,Günter Kostka,Attila Braun,Alexander Pfeifer,Peter D. Yurchenco,Reinhard Fässler +9 more
TL;DR: Data show that mammalian ILK modulates actin rearrangements at integrin-adhesion sites and expression of a mutant ILK lacking kinase activity and/or paxillin binding in ILK-deficient fibroblasts can rescue cell spreading, F-actin organization, FA formation, and proliferation.
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Tenomodulin is necessary for tenocyte proliferation and tendon maturation.
TL;DR: The results suggest that Tnmd is a regulator of tenocyte proliferation and is involved in collagen fibril maturation but do not confirm an in vivo involvement of TnMD in angiogenesis.
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Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin system.
TL;DR: This study examines the role of integrins in MSC differentiation, attachment to coating materials, survival on scaffolds and neoplastic transformation, and the consequences of integrin dysregulation.
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Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy
Denitsa Docheva,Daniela Padula,Daniela Padula,Cvetan Popov,Wolf Mutschler,Hauke Clausen-Schaumann,Hauke Clausen-Schaumann,Matthias Schieker +7 more
TL;DR: This study shows a direct comparison between the morphometric and biophysical features of different human cell types derived from normal and pathological bone, and manifests the opinion that along with RNA, proteomic and functional research, morphological and biomechanical characterization of cells also reveals novel cell features and interrelationships.