Derek L. Stirewalt

TL;DR: In this paper , the authors evaluated the annotated lncRNA landscape by transcript sequencing of 1,298 pediatric and 96 adult acute myeloid leukemia (AML) specimens and found that lncScores added to overall classification accuracy with at least comparable predictive performance to current stratification methods that rely on multiple assays.

TL;DR: In this article , the N6-methyladenosine (m6A) mRNA methyltransferase (MTase) complex was found to be required for human erythropoiesis in bone marrow-derived and G-CSF-mobilized CD34+ cells.

TL;DR: In this paper, a method for assessing exposure to ionizing radiation comprising the steps of (a) measuring the RNA expression level of certain biomarker genes in a biological sample; (b) correcting the RNA expressions of the measured biomarker in step (a), to a reference standard or threshold value, and (c) comparing the RNA expressed level of the biomarker measured in step(a) and corrected in accordance with step(b) to the corrected expression of a calibration sample or threshold values, wherein a difference in expression level between the biomarkers in the biological sample and the calibration

TL;DR: In this paper , the authors propose a method to solve the problem of "not available" data: https://www.youtube.com/watch/watch?feature=youtu.

TL;DR: In this paper , a focused drug screen using inhibitors targeting different DNA damage response pathways and drugs that inhibit DNA replication or DNA metabolic processes was performed to identify novel therapeutic targets in SF-mutant myeloid malignancies.