T
Thomas R. Chauncey
Researcher at University of Washington
Publications - 167
Citations - 13726
Thomas R. Chauncey is an academic researcher from University of Washington. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 58, co-authored 165 publications receiving 13262 citations. Previous affiliations of Thomas R. Chauncey include Stanford University & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects
Peter A. McSweeney,Peter A. McSweeney,Peter A. McSweeney,Dietger Niederwieser,Dietger Niederwieser,Dietger Niederwieser,Judith A. Shizuru,Judith A. Shizuru,Judith A. Shizuru,Brenda M. Sandmaier,Brenda M. Sandmaier,Brenda M. Sandmaier,Arthur J. Molina,Arthur J. Molina,Arthur J. Molina,David G. Maloney,David G. Maloney,David G. Maloney,Thomas R. Chauncey,Thomas R. Chauncey,Thomas R. Chauncey,Ted Gooley,Ted Gooley,Ted Gooley,U Hegenbart,U Hegenbart,U Hegenbart,Richard A. Nash,Richard A. Nash,Richard A. Nash,Jerald P. Radich,Jerald P. Radich,Jerald P. Radich,John L. Wagner,John L. Wagner,John L. Wagner,Steven Minor,Steven Minor,Steven Minor,Frederick R. Appelbaum,Frederick R. Appelbaum,Frederick R. Appelbaum,William I. Bensinger,William I. Bensinger,William I. Bensinger,Eileen Bryant,Eileen Bryant,Eileen Bryant,Mary E.D. Flowers,Mary E.D. Flowers,Mary E.D. Flowers,George E. Georges,George E. Georges,George E. Georges,F. Carl Grumet,F. Carl Grumet,F. Carl Grumet,Hans-Peter Kiem,Hans-Peter Kiem,Hans-Peter Kiem,Beverly Torok-Storb,Beverly Torok-Storb,Beverly Torok-Storb,Cong Yu,Cong Yu,Cong Yu,Karl G. Blume,Karl G. Blume,Karl G. Blume,Rainer Storb,Rainer Storb,Rainer Storb +71 more
TL;DR: A novel allografting approach, based on the use of postgrafting immunosuppression to control graft rejection and GVHD, has dramatically reduced the acute toxicities of allogRAFTing.
Journal ArticleDOI
Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers
William I. Bensinger,Paul J. Martin,Barry E. Storer,Reginald A. Clift,Steven J. Forman,Robert S. Negrin,Ashwin Kashyap,Mary E.D. Flowers,K Lilleby,Thomas R. Chauncey,Rainer Storb,Frederick R. Appelbaum +11 more
TL;DR: In patients given high-dose chemotherapy, with or without radiation, for the treatment of hematologic cancer,allogeneic peripheral-blood cells used for hematopoietic rescue restore blood counts faster than allogeneic bone marrow, without increasing the risk of graft-versus-host disease.
Journal ArticleDOI
Bone Marrow Transplants from Unrelated Donors for Patients with Chronic Myeloid Leukemia
John A. Hansen,Ted Gooley,Paul J. Martin,Frederick R. Appelbaum,Thomas R. Chauncey,Reginald A. Clift,Effie W. Petersdorf,Jerald P. Radich,Jean E. Sanders,Rainer Storb,Keith M. Sullivan,Claudio Anasetti +11 more
TL;DR: Transplantation of marrow from an HLA-matched, unrelated donor is safe and effective therapy for selected patients with chronic myeloid leukemia.
Journal ArticleDOI
Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases
Dietger Niederwieser,Michael B. Maris,Judith A. Shizuru,Effie W. Petersdorf,Ute Hegenbart,Brenda M. Sandmaier,David G. Maloney,Barry E. Storer,Thoralf Lange,Thomas R. Chauncey,Michael W. Deininger,Wolfram Pönisch,Claudio Anasetti,Ann E. Woolfrey,Marie Térèse Little,Karl G. Blume,Peter A. McSweeney,Rainer Storb +17 more
TL;DR: HCT from HLA-matched or mismatched unrelated donors can be performed with a reduced intensity conditioning regimen in patients ineligible for conventional HCT, according to preclinical studies.
Journal ArticleDOI
Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma
David G. Maloney,Arthur J. Molina,Firoozeh Sahebi,Keith Stockerl-Goldstein,Brenda M. Sandmaier,William I. Bensinger,Barry E. Storer,Ute Hegenbart,George Somlo,Thomas R. Chauncey,Benedetto Bruno,Frederick R. Appelbaum,Karl G. Blume,Stephen J. Forman,Peter A. McSweeney,Rainer Storb +15 more
TL;DR: Despite being evaluated in elderly patients with MM, this 2-step approach has reduced the acute toxicities of allogeneic HCT while achieving potent antitumor activities.