D
Derrick H. Lenz
Researcher at Princeton University
Publications - 6
Citations - 2025
Derrick H. Lenz is an academic researcher from Princeton University. The author has contributed to research in topics: Quorum sensing & Vibrio cholerae. The author has an hindex of 6, co-authored 6 publications receiving 1919 citations. Previous affiliations of Derrick H. Lenz include University of Cincinnati & Howard Hughes Medical Institute.
Papers
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Journal ArticleDOI
The Small RNA Chaperone Hfq and Multiple Small RNAs Control Quorum Sensing in Vibrio harveyi and Vibrio cholerae
Derrick H. Lenz,Kenny C. Mok,Brendan N. Lilley,Rahul V. Kulkarni,Ned S. Wingreen,Bonnie L. Bassler +5 more
TL;DR: It is proposed that Hfq, together with four candidate sRNAs, creates an ultrasensitive regulatory switch that controls the critical transition into the high cell density, quorum-sensing mode.
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Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae
TL;DR: This report identifies and characterize the genes encoding an additional V. cholerae autoinducer synthase and its cognate sensor and shows that in V.cholerae these communication systems converge to control virulence.
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CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae
TL;DR: In this article, the authors show that the VarS/VarA-CsrA/BCD system converges with the V. cholerae quorum-sensing systems to regulate the expression of the quorum regulatory RNAs.
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The small nucleoid protein Fis is involved in Vibrio cholerae quorum sensing.
TL;DR: The nucleoid protein Fis is identified as playing a major role in the V. cholerae quorum‐sensing circuit and fulfils the predictions required to be the putative additional component that inputs information into the cascade.
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Phagocytosed Bordetella pertussis fails to survive in human neutrophils
TL;DR: Data suggest that phagocytosed B. pertussis bacteria are killed by human neutrophils, in contrast to previous reports.