Devang Mehta

TL;DR: This study highlights the risks associated with CRISPR-Cas9 virus immunity in eukaryotes given that the mutagenic nature of the system generates viral escapes in a short time period and in-depth analysis of virus populations represents a template for future studies analyzing virus escape from anti-viral CRISpr transgenics.

TL;DR: It is demonstrated that CRISPR-Cas9–mediated targeted mutagenesis of two genes involved in amylose biosynthesis, PROTEIN TARGETing to STARCH (PTST1) or GRANULE BOUND STARCH SYNTHASE (GBSS), can reduce or eliminate amylOSE content in root starch.

TL;DR: Owing to the present constraints of long-read single-molecule sequencing, the accuracy of circular virus and eccDNA sequences generated by the CIDER-Seq method scales with sequence length, and the greatest accuracy is obtained for molecules <10 kb long.

TL;DR: This work encourages all conference organizers, funders and institutions who are able to do so to consider how they can mitigate the unintended consequences of conference and travel cancellations and provides seven recommendations for how this could be achieved.

TL;DR: Publishers, reviewers and other members of the scientific community must fight science’s preference for positive results — for the benefit of all, says Devang Mehta.