D
Diego Albani
Researcher at Mario Negri Institute for Pharmacological Research
Publications - 190
Citations - 13004
Diego Albani is an academic researcher from Mario Negri Institute for Pharmacological Research. The author has contributed to research in topics: Bipolar disorder & Population. The author has an hindex of 35, co-authored 178 publications receiving 10355 citations. Previous affiliations of Diego Albani include National Research Council.
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Journal ArticleDOI
Microbiota-Host Immunity Communication in Neurodegenerative Disorders: Bioengineering Challenges for In Vitro Modeling.
TL;DR: In this article, a review focused on microbiota-immunity-central nervous system (CNS) communication and showed how gut and oral microbiota populations trigger immune cells, propagating inflammation from the periphery to the cerebral parenchyma, thus contributing to the onset and progression of neurodegeneration.
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Alteration of SREBP activation in liver of trisomy 21 fetuses.
Luisa Diomede,Mario Salmona,Diego Albani,M. Bianchi,Alessandra Bruno,Sarah Salmona,Umberto Nicolini +6 more
TL;DR: It is reported here for the first time that SREBP-1 and SRE BP-2 are present in human fetal liver and their activation follows a different regulatory pattern.
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The Treviso Dementia (TREDEM) Study: A Biomedical, Neuroradiological, Neuropsychological and Social Investigation of Dementia in North-Eastern Italy.
Maurizio Gallucci,E Mariotti,D Saraggi,T Stecca,MG Oddo,C. Bergamelli,Paolo Boldrini,Stefano Mazzuco,Fausta Ongaro,P Mecocci,F Paola Di,Matteo Bendini,Gianluigi Forloni,Diego Albani,Piero Antuono,Livio Caberlotto,Andrea Zanardo,Marinella Siculi,G.B. Gajo,Elisabetta Durante,G Buscato +20 more
TL;DR: Results obtained from the preliminary analyses conducted in the TREDEM study suggest that the database will support the accomplishment of important goals in understanding the nature of cognitive frailty and neurodegenerative diseases.
Journal Article
Endotoxin regulates the maturation of sterol regulatory element binding protein-1 through the induction of cytokines
TL;DR: Endotoxin raised cholesterol levels and stimulated the maturation of hepatic SREBP-1 in both normal and cholesterol-fed mice, indicating that the lipogenic effect of LPS was independent of endogenous sterol levels and that the transcriptional activation of cholesterol biosynthesis may be part of the acute-phase response.
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The role of single-nucleotide variants of the energy metabolism-linked genes SIRT3, PPARGC1A and APOE in amyotrophic lateral sclerosis risk
Diego Albani,Elisabetta Pupillo,Elisa Bianchi,Armando Chierchia,Rosalba Martines,Gianluigi Forloni,Ettore Beghi +6 more
TL;DR: Findings suggest a contribution to ALS risk of genetic and environmental factors involved in energy metabolism, and stress the importance of a multifactorial analysis for evaluating this risk.