D
Diego Ruano
Researcher at University of Seville
Publications - 60
Citations - 9428
Diego Ruano is an academic researcher from University of Seville. The author has contributed to research in topics: GABAA receptor & Protein subunit. The author has an hindex of 31, co-authored 60 publications receiving 7902 citations. Previous affiliations of Diego Ruano include Centre national de la recherche scientifique & Spanish National Research Council.
Papers
More filters
Journal ArticleDOI
Distribution of NADPH-diaphorase and nitric oxide synthase reactivity in the central nervous system of the goldfish (Carassius auratus).
TL;DR: The aim of the present work was to systematically study the distribution of cell producing nitric oxide in the goldfish brain and found labeled cells widely distributed in brain and spinal cord, concluding that the nitrergic system is roughly similar from fish to mammals.
Journal ArticleDOI
Prevalence between different α subunits performing the benzodiazepine binding sites in native heterologous GABAA receptors containing the α2 subunit
TL;DR: The results demonstrated the existence of a differential dominance between the different α subunits performing the benzodiazepine binding sites in the native GABAA receptors.
Journal ArticleDOI
Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex.
TL;DR: The results demonstrate that the benzodiazepine binding sites and the GABA binding sites of the GABAA receptor complex from rat prefrontal cortical membranes are differentially affected by the aging process.
Journal ArticleDOI
Age and meloxicam attenuate the ischemia/reperfusion-induced down-regulation in the NMDA receptor genes
Sheyla Montori,Severiano Dos-Anjos,Beatriz Martínez-Villayandre,Marta Regueiro-Purriños,José M. Gonzalo-Orden,Diego Ruano,Arsenio Fernández-López +6 more
TL;DR: In the assays of ischemia/reperfusion followed by a treatment with the anti-inflammatory agent meloxicam, it was observed that ischemic insult was unable to elicit changes in the NMDAR transcription, thus suggesting that inflammation plays a crucial role in the transcriptional control of these genes.
Journal ArticleDOI
Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex
TL;DR: The results demonstrate the absence of modifications in Type I or total benzodiazepine binding sites of the GABAA receptor complex from adult and aged cortical membranes in Fischer or Wistar rats.