D
Dieter Vandenheuvel
Researcher at University of Antwerp
Publications - 36
Citations - 1828
Dieter Vandenheuvel is an academic researcher from University of Antwerp. The author has contributed to research in topics: Bacteriophage & Phage therapy. The author has an hindex of 20, co-authored 34 publications receiving 1277 citations. Previous affiliations of Dieter Vandenheuvel include Katholieke Universiteit Leuven & Catholic University of Leuven.
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Journal ArticleDOI
Drying techniques of probiotic bacteria as an important step towards the development of novel pharmabiotics.
TL;DR: The characteristics, but also the viability results obtained by the most relevant drying techniques in the probiotic industry are described to facilitate the deliberate choice of drying process and protection strategy for specific probiotic and pharmabiotic applications.
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T4-Related Bacteriophage LIMEstone Isolates for the Control of Soft Rot on Potato Caused by ‘Dickeya solani’
Evelien M. Adriaenssens,Johan Van Vaerenbergh,Dieter Vandenheuvel,Vincent Dunon,Pieter-Jan Ceyssens,Maurice De Proft,Andrew M. Kropinski,Andrew M. Kropinski,Jean-Paul Noben,Martine Maes,Rob Lavigne +10 more
TL;DR: The bacterium ‘Dickeya solani’, an aggressive biovar 3 variant of Dickeya dianthicola, causes rotting and blackleg in potato, is controlled using bacteriophage therapy and two closely related and specific phages isolated and characterized are deemed suitable and promising for use in phage therapy.
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Bacteriophage Therapy: Advances in Formulation Strategies and Human Clinical Trials
TL;DR: Though hurdles for efficient treatment remain, these trials hold promise for future phase III clinical trials, and additional research on formulation strategies and the stability of phage-based drugs will be of key importance, especially with phage therapy advancing toward phase III trials.
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Two Phages, phiIPLA-RODI and phiIPLA-C1C, Lyse Mono- and Dual-Species Staphylococcal Biofilms
TL;DR: It is confirmed that lytic bacteriophages can be efficient biofilm-disrupting agents, supporting their potential as antimicrobials against staphylococcal infections.
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Feasibility of spray drying bacteriophages into respirable powders to combat pulmonary bacterial infections
Dieter Vandenheuvel,Abhishek Singh,Katrien Vandersteegen,Jochen Klumpp,Rob Lavigne,Guy Van den Mooter +5 more
TL;DR: Even though the parameters were not optimized for spray drying all phages, it was demonstrated that spray drying phages with this industrial relevant and scalable set up was possible and the resulting powders had desirable size ranges for pulmonary delivery of phage with dry powder inhalers (DPIs).