Showing papers by "Dinesh K. Patel published in 2018"

A Review on Pharmacological and Analytical Aspects of Naringenin

Abstract: Flavonoids are a widely distributed group of phytochemicals having benzo-pyrone nucleus, and more than 4,000 different flavonoids have been described and categorized into flavonols, flavones, flavanones, isoflavones, catechins and anthocyanidins. Flavonoids occurs naturally in fruits, vegetables, nuts, and beverages such as coffee, tea, and red wine, as well as in medical herbs. Flavonoids are responsible for the different colors of plant parts and are important constituents of the human diet. Flavanoids have different pharmacological activities, such as antioxidant, anti-allergic, antibacterial, anti-inflammatory, antimutagenic and anticancer activity. Naringenin belongs to the flavanones and is mainly found in fruits (grapefruit and oranges) and vegetables. Pharmacologically, it has anticancer, antimutagenic, anti-inflammatory, antioxidant, antiproliferative and antiatherogenic activities. Naringenin is used for the treatments of osteoporosis, cancer and cardiovascular diseases, and showed lipid-lowering and insulin-like properties. In the present review, detailed pharmacological and analytical aspects of naringenin have been presented, which revealed the impressive pharmacological profile and the possible usefulness in the treatment of different types of diseases in the future. The information provided in this communication will act as an important source for development of effective medicines for the treatment of various disorders.

Monitoring of Air Pollution in Different Regions Along Road Network, Jharia Coalfield, Dhanbad, India

Abstract: Air pollution levels were measured during October, 2014 along the road network at Jharia Coalfield, Dhanbad, Jharkhand, India. The monitored PM concentrations were designated as PM10 and PM2.5 for aerodynamic diameter smaller than 10 and 2.5 μm, respectively. Concentration of PM10 and PM2.5 in mining area such as BMO, GDR, and KMO were about two times higher than ISM (non-mining area). Variation in the peaks of PM10 and PM2.5 concentrations were well correlated with the traffic volume count (TVC) at all monitoring locations except GDR due to the transportation of coal using Hyva truck and associated activities due to the mining industry. Concentrations of PM10 and PM2.5 exceed 24-hour standards as per Indian national ambient air quality standards (NAAQS 2009) as well as World Health Organization (WHO 2005) at all locations in the mining area. Based on the air quality index, air qualities were falling under very highly polluted category mainly at BMO, GDR, KDH, KMO, and DHR.