D
Do Hyun Kim
Researcher at Hanyang University
Publications - 62
Citations - 1062
Do Hyun Kim is an academic researcher from Hanyang University. The author has contributed to research in topics: Inflammation & T cell. The author has an hindex of 15, co-authored 58 publications receiving 796 citations. Previous affiliations of Do Hyun Kim include University of Pennsylvania & Seoul National University.
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Journal ArticleDOI
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Sangho Lim,Sangho Lim,Won Ju Kim,Won Ju Kim,Yeon-ho Kim,Yeon-ho Kim,Sohee Lee,Ja Hyun Koo,Ja Hyun Koo,Jung Ah Lee,Jung Ah Lee,Heeseok Yoon,Heeseok Yoon,Do Hyun Kim,Do Hyun Kim,Hong Jai Park,Hong Jai Park,Hye Mi Kim,Hong Gyun Lee,Hong Gyun Lee,Ji Yun Kim,Ji Yun Kim,Jae Ung Lee,Jae Ung Lee,Jae Hun Shin,Lark Kyun Kim,Junsang Doh,Hongtae Kim,Sang Kyou Lee,Alfred L. M. Bothwell,Minah Suh,Je-Min Choi,Je-Min Choi +32 more
TL;DR: It is demonstrated that d NP2 is a blood–brain barrier-permeable peptide and dNP2-ctCTLA-4 could be an effective agent for treating CNS inflammatory diseases such as MS.
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IL-18 induces emphysema and airway and vascular remodeling via IFN-γ, IL-17A, and IL-13.
Min-Jong Kang,Je-Min Choi,Bo Hye Kim,Chang-Min Lee,Won-Kyung Cho,Gina Choe,Do Hyun Kim,Chun Geun Lee,Jack A. Elias +8 more
TL;DR: The spectrum of inflammatory, parenchymal, airway, and vascular alterations that are induced by pulmonary IL-18 is defined; the similarities between these responses and the lesions in COPD are highlighted; and the selective roles that type 1, type 2, and type 17 responses play in the generation of IL- 18-induced pathologies are defined.
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Insights into the Role of Follicular Helper T Cells in Autoimmunity
TL;DR: Regulation of TFH cell differentiation and the GC reaction via miRNA and TFR cells could be important regulatory mechanisms for maintaining immune tolerance and preventing autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).
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Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Do Hyun Kim,Hong Jai Park,Sangho Lim,Sangho Lim,Ja Hyun Koo,Ja Hyun Koo,Hong Gyun Lee,Hong Gyun Lee,Jin Ouk Choi,Ji Hoon Oh,Sang Jun Ha,Min-Jong Kang,Chang-Min Lee,Chun Geun Lee,Chun Geun Lee,Jack A. Elias,Je-Min Choi,Je-Min Choi +17 more
TL;DR: It is shown that Chi3l1 inhibits the T cell response by negatively regulating their activation and that, in a mouse model of melanoma, T cell-targeted silencing of Chi 3l1 results in reduced lung metastasis.
Journal ArticleDOI
UV-responsive nano-sponge for oil absorption and desorption
Do Hyun Kim,Min Chan Jung,So-Hye Cho,Sang Hoon Kim,Ho-Young Kim,Heon Ju Lee,Kyu Hwan Oh,Myoung-Woon Moon +7 more
TL;DR: A novel method is reported to fabricate a nano-sponge which is composed of hydrophobic hydrocarbon and hydrophilic TiO2 nanoparticles for oil absorption or desorption that are responsive to UV irradiation that can be applied for oil-water separation, oil spill cleanup and reuse of spilled oil.