Chang-Min Lee

TL;DR: The curcumin-treated DC showed an impaired induction of Th1 responses and a normal cell-mediated immune response, which provides new insight into the immunopharmacological role ofCurcumin in impacting on the DC.

TL;DR: IL-13Rα2 is a GH 18 receptor that plays a critical role in Chi3l1 effector responses and regulates oxidant injury, apoptosis, pyroptosis, inflammasome activation, antibacterial responses, melanoma metastasis, and TGF-β1 production via IL-13rα2-dependent mechanisms.

TL;DR: Evidence is provided that Quercetin plays a critical role in the amelioration of the pathogenetic process of asthma in mice, and new insight is provided into the immunopharmacological role of QuercETin in terms of its effects in a murine model of asthma.

TL;DR: This model played a protective role in injury by ameliorating inflammation and cell death, and a profibrotic role in the repair phase by augmenting alternative macrophage activation, fibroblast proliferation, and matrix deposition, and these studies demonstrate that CHI3L1 is stimulated in IPF, where it represents an attempt to diminish injury and induce repair.

TL;DR: It is revealed that lycopene significantly attenuates the phenotypic and functional maturation of murine BM‐DC, especially in lipopolysaccharide‐induced DC maturation, and is able to inhibit mitogen‐activated protein kinases and the transcription factor, nuclear factor‐κB.