D
Dominique Bron
Researcher at Université libre de Bruxelles
Publications - 372
Citations - 15450
Dominique Bron is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Mesenchymal stem cell & Stromal cell. The author has an hindex of 56, co-authored 357 publications receiving 13785 citations. Previous affiliations of Dominique Bron include Free University of Brussels & Institut Jules Bordet.
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Journal ArticleDOI
Autologous Bone Marrow Transplantation as Compared with Salvage Chemotherapy in Relapses of Chemotherapy-Sensitive Non-Hodgkin's Lymphoma
Thierry Philip,Cesare Guglielmi,Anton Hagenbeek,Riet Somers,H. Van der Lelie,Dominique Bron,Pieter Sonneveld,Christian Gisselbrecht,Jean-Yves Cahn,Jean Luc Harousseau +9 more
TL;DR: Treatment with high-dose chemotherapy and autologous bone marrow transplantation increases event-free and overall survival in patients with chemotherapy-sensitive non-Hodgkin's lymphoma in relapse.
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CD4+ follicular helper T cell infiltration predicts breast cancer survival
Chunyan Gu-Trantien,Sherene Loi,Soizic Garaud,Carole Equeter,Myriam Libin,Alexandre de Wind,Marie Ravoet,Hélène Le Buanec,Catherine Sibille,Germain Manfouo-Foutsop,Isabelle Veys,Benjamin Haibe-Kains,Sandeep Singhal,Stefan Michiels,Françoise Rothé,Roberto Salgado,Hugues Duvillier,Michail Ignatiadis,Christine Desmedt,Dominique Bron,Denis Larsimont,Martine Piccart,Christos Sotiriou,Karen Willard-Gallo +23 more
TL;DR: The identification of CD4⁺ Tfh cells in breast cancer suggests that they are an important immune element whose presence in the tumor is a prognostic factor.
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Mesenchymal stem cells derived from CD133-positive cells in mobilized peripheral blood and cord blood: proliferation, Oct4 expression, and plasticity.
Tatiana Tondreau,Nathalie Meuleman,Alain Delforge,Marielle Dejeneffe,Rita Leroy,Martine Massy,Christine Mortier,Dominique Bron,Laurence Lagneaux +8 more
TL;DR: The selection of CD133‐positive cells enabled us to obtain a homogeneous population of MSCs from UCB and MPB, and these sources may have a major clinical importance thanks to their easy accessibility.
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Chronic Lymphocytic Leukemic B Cells But Not Normal B Cells Are Rescued From Apoptosis by Contact With Normal Bone Marrow Stromal Cells
TL;DR: Contact between B-CLL cells and bone marrow stromal cells seems to play a major role in the accumulation and survival of B- CLL cells in the bone marrow, and direct contact between leukemic cells and stronal cells was found to be essential for inhibition of leukeMIC cell apoptosis.
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Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression.
TL;DR: It is reported here that IL-4 protects the B-CLL cells from death by apoptosis (programmed cell death [PCD]), and it is proposed thatIL-4 has an essential role in the pathogenesis of CLL disease, by preventing both the death and the proliferation of the malignant B cells.