D
Dominique Farabos
Researcher at University of Paris
Publications - 5
Citations - 48
Dominique Farabos is an academic researcher from University of Paris. The author has contributed to research in topics: Insulin receptor & Thermogenesis. The author has an hindex of 2, co-authored 5 publications receiving 12 citations.
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Journal ArticleDOI
The Goto-Kakizaki rat is a spontaneous prototypical rodent model of polycystic ovary syndrome.
Camille Bourgneuf,Camille Bourgneuf,Danielle Bailbe,Antonin Lamaziere,Charlotte Dupont,Charlotte Dupont,Marthe Moldes,Marthe Moldes,Dominique Farabos,Natacha Roblot,Natacha Roblot,Camille Gauthier,Camille Gauthier,Emmanuelle Mathieu d'Argent,Emmanuelle Mathieu d'Argent,Joëlle Cohen-Tannoudji,Danielle Monniaux,Bruno Fève,Bruno Fève,Jamileh Movassat,Nathalie di Clemente,Nathalie di Clemente,Chrystèle Racine,Chrystèle Racine +23 more
TL;DR: In this paper, female Goto-Kakizaki (GK) rats, a type 2 diabetes mellitus model, encapsulate naturally all the reproductive and metabolic hallmarks of lean women with polycystic ovarian syndrome at puberty and in adulthood.
Journal ArticleDOI
Fat gain differs by sex and hormonal status in persons living with suppressed HIV switched to raltegravir/etravirine.
Lambert Assoumou,Chrystèle Racine,Soraya Fellahi,Antonin Lamaziere,Dominique Farabos,Lydie Beniguel,Jean-Philippe Bastard,Bruno Fève,Séverine Gibowski,Christine Katlama,Dominique Costagliola,Jacqueline Capeau +11 more
TL;DR: From baseline to 48/96-week, women with ovarian reserve were protected from raltegravir/etravirine-induced weight/fat gain and associated insulin-resistance while peri/postmenopausal women increased weight, fat and insulin-Resistance as did men.
Journal ArticleDOI
Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice.
Sarah Saget,Rong Cong,Lyvianne Decourtye,Marie-Laure Endale,Laetitia Martinerie,Clemence Girardet,Claire Perret,Maud Clemessy,P Leneuve,Laetitia Dinard,Badreddine Mohand Oumoussa,Dominique Farabos,Antonin Lamaziere,Marc Lombès,Marthe Moldes,Bruno Fève,David-Alexandre Trégouët,Yves Le Bouc,Laurent Kappeler,Laurent Kappeler +19 more
TL;DR: Molecular alterations to the insulin signaling pathway with an early onset were observed in the livers of adult IUGR-N mice, nine months before the appearance of insulin resistance, suggesting a possible role for this miRNA as an early circulating biomarker of metabolic fate of potential use for precision medicine.
Journal ArticleDOI
Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy
Camille Gamblin,Christine Rouault,Amélie Lacombe,Francina Langa-Vives,Dominique Farabos,Antonin Lamaziere,Karine Clément,Emmanuel L. Gautier,Laurent Yvan-Charvet,Isabelle Dugail +9 more
TL;DR: It is demonstrated that adipose LAL drives tissue cholesterol homeostasis and impacts BAT metabolism, suggesting beneficial LAL activation in anti-obesity approaches aimed at reactivating thermogenic energy expenditure.
Journal ArticleDOI
Découverte du premier modèle pré-clinique développant spontanément un syndrome des ovaires polykystiques
Camille Bourgneuf,Danielle Bailbe,Antonin Lamaziere,Charlotte Dupont,Marthe Moldes,Dominique Farabos,Natacha Roblot,Camille Gauthier,Emmanuelle Mathieu d'Argent,Joëlle Cohen-Tannoudji,Danielle Monniaux,Bruno Fève,Jamileh Movassat,Nathalie di Clemente,Chrystèle Racine +14 more