D
Dominique Mahe
Researcher at Zoetis
Publications - 19
Citations - 1138
Dominique Mahe is an academic researcher from Zoetis. The author has contributed to research in topics: Porcine circovirus & Circovirus. The author has an hindex of 9, co-authored 18 publications receiving 1108 citations.
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Journal ArticleDOI
Differential recognition of ORF2 protein from type 1 and type 2 porcine circoviruses and identification of immunorelevant epitopes.
Dominique Mahe,Philippe Blanchard,Catherine Truong,Claire Arnauld,P Le Cann,Roland Cariolet,François Madec,Emmanuel Albina,André Jestin +8 more
TL;DR: In order to discriminate between common and type-specific antigens, an immunocytological approach was used following transfections with cloned circovirus DNAs, as well as recombinant proteins expressed by either baculovirus or plasmid vectors.
Journal ArticleDOI
Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins.
Philippe Blanchard,Dominique Mahe,Roland Cariolet,A. Keranflec'h,M. A. Baudouard,P Cordioli,Emmanuel Albina,André Jestin +7 more
TL;DR: In this paper, a prime-boost protocol was used to immunize pigs against post-weaning multisystemic wasting syndrome (PMWS), a recently described disease of young pigs.
Protection of swine against Post-weaning Multisystemic Wasting Syndrome (PMWS) by Porcine Circovirus Type 2 (PCV2) proteins.
Philippe Blanchard,Dominique Mahe,Roland Cariolet,A. Keranflec'h,M. A. Baudouard,Emmanuel Albina,André Jestin +6 more
TL;DR: A specific PCV2 vaccine candidate has been developed, and protection induced by a subunit vaccine was even better than the one induced by DNA vaccine, sincePCV2 replication was completely inhibited.
Journal ArticleDOI
Post-weaning multisystemic wasting syndrome (PMWS) in pigs in France: Clinical observations from follow-up studies on affected farms.
François Madec,Eric Eveno,P Morvan,L Hamon,Philippe Blanchard,Roland Cariolet,N. Amenna,H. Morvan,Catherine Truong,Dominique Mahe,E Albina,André Jestin +11 more
TL;DR: A disease affecting weaned pigs and known as Postweaning Multisystemic Wasting Syndrome (PMWS) is described on French farms with a strong litter effect on disease susceptibility and the environment was suspected as an important determining factor for the effect of PMWS in the herds.
Journal ArticleDOI
An ORF2 protein-based ELISA for porcine circovirus type 2 antibodies in post-weaning multisystemic wasting syndrome.
Ph. Blanchard,Dominique Mahe,Roland Cariolet,Catherine Truong,M. Le Dimna,Claire Arnauld,Nicolas Rose,Eric Eveno,Emmanuel Albina,François Madec,André Jestin +10 more
TL;DR: The specificity of the ELISA for detection ofPCV2 antibodies was demonstrated in sera from pigs experimentally infected with PCV1, PCV2 and other swine viruses, and the semi-quantitative nature of the test was evaluated versus an immunoperoxidase monolayer assay.