D
Dominique Maraninchi
Researcher at French Institute of Health and Medical Research
Publications - 189
Citations - 8309
Dominique Maraninchi is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transplantation & Bone marrow. The author has an hindex of 47, co-authored 188 publications receiving 8108 citations. Previous affiliations of Dominique Maraninchi include Roussel Uclaf.
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Randomized Phase II Trial of the Efficacy and Safety of Trastuzumab Combined With Docetaxel in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Administered As First-Line Treatment: The M77001 Study Group
M Marty,Francesco Cognetti,Dominique Maraninchi,Raymond Snyder,Louis Mauriac,Michèle Tubiana-Hulin,Stephen Chan,David Grimes,Antonio Antón,Anna Lluch,John Kennedy,Kenneth J. O'Byrne,Pierfranco Conte,Michael D. Green,Carol Ward,Karen Mayne,Jean-Marc Extra +16 more
TL;DR: Tastuzumab combined with docetaxel is superior to docetAXel alone as first-line treatment of patients with HER2-positive MBC in terms of overall survival, response rate, response duration, time to progression, and time to treatment failure, with little additional toxicity.
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Impact of T-cell depletion on outcome of allogeneic bone-marrow transplantation for standard-risk leukaemias.
Dominique Maraninchi,Didier Blaise,Bernard Rio,Véronique Leblond,F. Dreyfus,Eliane Gluckman,Denis Guyotat,Jose-Luis Pico,Mauricette Michallet,N. Ifrah,A. Bordigoni +10 more
TL;DR: Without better control of host immunity and of the residual leukaemia T-cell depletion of the marrow, BMT should not be pursued in standard-risk patients.
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Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers
François Bertucci,Pascal Finetti,Nathalie Cervera,Emmanuelle Charafe-Jauffret,Emilie Mamessier,José Adélaïde,Stéphane Debono,Gilles Houvenaeghel,Dominique Maraninchi,Patrice Viens,Colette Charpin,Jocelyne Jacquemier,Daniel Birnbaum +12 more
TL;DR: In this paper, the authors compared gene expression profiles of 22 MBCs and 44 grade III DBCs using whole-genome oligonucleotide microarrays and found that 95% of the MBC cells display a basal profile similar to that of basal breast cancer.
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Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: a European survey of the role of marrow purging.
Norbert-Claude Gorin,Philippe Aegerter,B. Auvert,Giovanna Meloni,Ah Goldstone,A Burnett,A. M. Carella,M Korbling,Patrick Hervé,Dominique Maraninchi +9 more
TL;DR: It is concluded that marrow purging with mafosfamide may be valuable for patients autografted early in first CR.
Journal ArticleDOI
Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission: a randomized trial of a busulfan-Cytoxan versus Cytoxan-total body irradiation as preparative regimen: a report from the Group d'Etudes de la Greffe de Moelle Osseuse.
Didier Blaise,Dominique Maraninchi,Eric Archimbaud,Josy Reiffers,Agnès Devergie,Jean-Pierre Jouet,Noel-Jean Milpied,M. Attal,Marie-Cécile Michallet,Norbert Ifrah +9 more
TL;DR: The present limitation of busulfan use in this setting is demonstrated, possibly due to probable individual variations in biodisponibility, and besides the anti-leukemic effect of preparative regimens, the progress accomplished in BMT management is pointed out.