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Don Corsmeier
Researcher at Nationwide Children's Hospital
Publications - 6
Citations - 174
Don Corsmeier is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Gene & Exome. The author has an hindex of 5, co-authored 6 publications receiving 131 citations. Previous affiliations of Don Corsmeier include The Research Institute at Nationwide Children's Hospital & Ohio State University.
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Journal ArticleDOI
Utilization of Whole Exome Sequencing to Identify Causative Mutations in Familial Congenital Heart Disease.
Stephanie LaHaye,Don Corsmeier,Madhumita Basu,Jessica Bowman,Sara Fitzgerald-Butt,Gloria Zender,Kevin Bosse,Kim L. McBride,Peter White,Vidu Garg +9 more
TL;DR: The findings demonstrate the clinical utility of WES to identify causative mutations in familial CHD and demonstrate the successful use of a CHD candidate gene list to allow for a more streamlined approach enabling rapid prioritization and identification of likely pathogenic variants from large WES data sets.
Journal ArticleDOI
Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve
Elizabeth M. Bonachea,Gloria Zender,Peter White,Peter White,Don Corsmeier,David L. Newsom,Sara Fitzgerald-Butt,Sara Fitzgerald-Butt,Vidu Garg,Vidu Garg,Kim L. McBride,Kim L. McBride +11 more
TL;DR: A pooling and targeted capture strategy was successfully developed that enabled rapid and cost effective next generation sequencing of target genes in a large patient cohort and suggests that BAV heritability is complex and polygenic.
Journal ArticleDOI
A genome-wide association study of congenital cardiovascular left-sided lesions shows association with a locus on chromosome 20
Neil A. Hanchard,Shanker Swaminathan,Kristine L. Bucasas,Dieter Furthner,Susan D. Fernbach,Mahshid S. Azamian,Xueqing Wang,Mark B. Lewin,Jeffrey A. Towbin,Lisa C.A. D'Alessandro,Shaine A. Morris,William J. Dreyer,Susan W. Denfield,Nancy A. Ayres,Wayne J. Franklin,Henri Justino,M. Regina Lantin-Hermoso,Elena C. Ocampo,Alexia B. Santos,Dhaval R. Parekh,Douglas Moodie,Aamir Jeewa,Emily J. Lawrence,Hugh D. Allen,Daniel J. Penny,Charles D. Fraser,James R. Lupski,Mojisola Popoola,Lalita Wadhwa,J. David Brook,Frances A. Bu'Lock,Shoumo Bhattacharya,Seema R. Lalani,Gloria Zender,Sara Fitzgerald-Butt,Sara Fitzgerald-Butt,Jessica Bowman,Jessica Bowman,Don Corsmeier,Don Corsmeier,Peter White,Peter White,Kelsey Lecerf,Gladys Zapata,Patricia P. Hernandez,Judith A. Goodship,Vidu Garg,Vidu Garg,Bernard Keavney,Suzanne M. Leal,Heather J. Cordell,John W. Belmont,Kim L. McBride,Kim L. McBride +53 more
TL;DR: Genome-wide heritability analysis using case-control genotyped SNPs suggested that the mean heritability of LSLs attributable to common variants is moderately high, consistent with previous assertions.
Journal ArticleDOI
In-frame de novo mutation in BICD2 in two patients with muscular atrophy and arthrogryposis.
Daniel C. Koboldt,Rama D. Kastury,Megan A. Waldrop,Benjamin J. Kelly,Theresa Mihalic Mosher,Theresa Mihalic Mosher,Heather M. McLaughlin,Don Corsmeier,Jonathan L. Slaughter,Jonathan L. Slaughter,Kevin M. Flanigan,Kevin M. Flanigan,Kim L. McBride,Kim L. McBride,Lakshmi Mehta,Richard K. Wilson,Richard K. Wilson,Peter White,Peter White +18 more
TL;DR: These findings support a broader phenotypic spectrum of BICD2 mutations that may include severe manifestations such as cerebral atrophy, seizures, dysmorphic facial features, and profound muscular atrophy.
Journal ArticleDOI
Human CRMP4 mutation and disrupted Crmp4 expression in mice are associated with ASD characteristics and sexual dimorphism
Atsuhiro Tsutiya,Yui Nakano,Emily Hansen-Kiss,Benjamin J. Kelly,Masugi Nishihara,Yoshio Goshima,Don Corsmeier,Peter White,Gail E. Herman,Ritsuko Ohtani-Kaneko +9 more
TL;DR: Results indicate a functional link between a case-specific, rare variant of one gene, Crmp4, and several characteristics of ASD, including sexual differences.