H
Hugh D. Allen
Researcher at Baylor College of Medicine
Publications - 30
Citations - 991
Hugh D. Allen is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Population & Sudden death. The author has an hindex of 11, co-authored 30 publications receiving 803 citations. Previous affiliations of Hugh D. Allen include Boston Children's Hospital.
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Journal ArticleDOI
Eteplirsen for the treatment of Duchenne muscular dystrophy
Jerry R. Mendell,Louise R. Rodino-Klapac,Zarife Sahenk,Kandice Roush,Loren Bird,Linda Lowes,Lindsay N. Alfano,Ann Maria Gomez,Sarah Lewis,Janaiah Kota,Vinod Malik,Kim Shontz,Christopher M. Walker,Kevin M. Flanigan,Marco Corridore,John R. Kean,Hugh D. Allen,Chris Shilling,Kathleen R. Melia,Peter Sazani,Jay B. Saoud,Edward M. Kaye +21 more
TL;DR: The authors used a double-blind placebo controlled protocol to test eteplirsen's ability to induce dystrophin production and improve distance walked on the 6-minute walk test (6MWT).
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Nebulized budesonide is as effective as nebulized adrenaline in moderately severe croup.
TL;DR: This study does not show any difference in efficacy and safety between neBulized budesonide and nebulized adrenaline in the treatment of acute upper airway obstruction in patients with moderately severe croup.
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Relation of Cardiac Dysfunction to Rhythm Abnormalities in Patients With Duchenne or Becker Muscular Dystrophies
David Y. Chiang,Hugh D. Allen,Jeffrey J. Kim,Santiago O. Valdes,Yunfei Wang,Ricardo H. Pignatelli,Timothy Lotze,Christina Y. Miyake,Christina Y. Miyake +8 more
TL;DR: Subgroup analysis of Holters from patients with DMD demonstrated that arrhythmias increased with decreasing ejection fraction regardless of age, but that age was also a significant predictor of arrhythmia development.
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Novel long QT syndrome-associated missense mutation, L762F, in CACNA1C-encoded L-type calcium channel imparts a slower inactivation tau and increased sustained and window current
Andrew P. Landstrom,Nicole J. Boczek,Dan Ye,Christina Y. Miyake,Caridad M. de la Uz,Hugh D. Allen,Michael J. Ackerman,Jeffrey J. Kim +7 more
TL;DR: The CACNA1C-L762F mutation is associated with development of LQTS through slower channel inactivation and increased sustained and window current, and is also associated with a younger age at presentation, higher QTc, and 2:1 AV block than isolated LQ TS-associated mutations.
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Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals.
Andrew P. Landstrom,Andrew L. Dailey-Schwartz,Jill A. Rosenfeld,Yaping Yang,Margaret J. McLean,Christina Y. Miyake,Santiago O. Valdes,Yuxin Fan,Hugh D. Allen,Daniel J. Penny,Jeffrey J. Kim +10 more
TL;DR: Variants of undetermined significances in CPVT-associated genes in WES genetic testing, in the absence of clinical suspicion for CPVT, are unlikely to represent markers of CPVT pathogenicity.