D
Donald R. Griffin
Researcher at University of Virginia
Publications - 33
Citations - 1687
Donald R. Griffin is an academic researcher from University of Virginia. The author has contributed to research in topics: Self-healing hydrogels & Tissue engineering. The author has an hindex of 11, co-authored 28 publications receiving 1134 citations. Previous affiliations of Donald R. Griffin include University of California & University of California, Berkeley.
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Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks
TL;DR: An injectable, interconnected microporous gel scaffold assembled from annealed microgel building blocks whose chemical and physical properties can be tailored by microfluidic fabrication facilitated cell migration that resulted in rapid cutaneous-tissue regeneration and tissue-structure formation within five days.
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Photodegradable macromers and hydrogels for live cell encapsulation and release.
TL;DR: By exploiting the differences in reactivity of two different o-NB linkers, this work quantitatively demonstrate the biased release of one stem cell population over another (red-fluorescent protein expressing hMSCs).
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Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Donald R. Griffin,Donald R. Griffin,Maani M. Archang,Chen-Hsiang Kuan,Westbrook M. Weaver,Jason S. Weinstein,An-Chieh Feng,Amber Ruccia,Elias Sideris,Vasileios Ragkousis,Jaekyung Koh,Maksim V. Plikus,Dino Di Carlo,Tatiana Segura,Tatiana Segura,Philip O. Scumpia,Philip O. Scumpia +16 more
TL;DR: D-peptide crosslinked MAP hydrogel (d-MAP) hastened material degradation in vivo and imparted significant tissue regeneration to healed cutaneous wounds, including increased tensile strength and hair neogenesis.
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Photodegradable Hydrogels to Generate Positive and Negative Features over Multiple Length Scales
TL;DR: Conjugation of a coumarin fluorophore to the o-NBE macromer enhances the sensitivity of the hydrogel to two-photon degradation, simultaneously incorporating fluorescence visualization with no added dye.
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Particle Hydrogels Based on Hyaluronic Acid Building Blocks
Elias Sideris,Donald R. Griffin,Yichen Ding,Shuoran Li,Westbrook M. Weaver,Dino Di Carlo,Tzung K. Hsiai,Tatiana Segura +7 more
TL;DR: Three orthogonal annealing chemistries based on an enzymatic reaction, light based radical polymerization, and amine/carboxylic acid based cross-linking are explored to demonstrate the versatility of particle hydrogels and explore potential physical differences between the approaches.