T
Tatiana Segura
Researcher at Duke University
Publications - 132
Citations - 9249
Tatiana Segura is an academic researcher from Duke University. The author has contributed to research in topics: Self-healing hydrogels & Gene delivery. The author has an hindex of 45, co-authored 130 publications receiving 7148 citations. Previous affiliations of Tatiana Segura include École Polytechnique Fédérale de Lausanne & California NanoSystems Institute.
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Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks
TL;DR: An injectable, interconnected microporous gel scaffold assembled from annealed microgel building blocks whose chemical and physical properties can be tailored by microfluidic fabrication facilitated cell migration that resulted in rapid cutaneous-tissue regeneration and tissue-structure formation within five days.
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Hydrogel microparticles for biomedical applications.
TL;DR: The techniques that are available for fabricating HMPs, as well as the multiscale behaviours of HMP systems and their functional properties are discussed, highlighting their advantages over traditional bulk hydrogels.
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In situ forming injectable hydrogels for drug delivery and wound repair.
TL;DR: This review highlights injectable therapeutic hydrogel biomaterials in the context of drug delivery and tissue regeneration for skin wound repair and provides an avenue to minimally invasively deliver therapeutic payloads, fill complex tissue defects, and induce the regeneration of damaged portions of the body.
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A novel intracellular protein delivery platform based on single-protein nanocapsules
Ming Yan,Juanjuan Du,Zhen Gu,Min Liang,Yufang Hu,Wenjun Zhang,Saul J. Priceman,Lily Wu,Z. Hong Zhou,Zheng Liu,Tatiana Segura,Yi Tang,Yunfeng Lu +12 more
TL;DR: A novel delivery platform based on nanocapsules consisting of a protein core and a thin permeable polymeric shell that can be engineered to either degrade or remain stable at different pHs is shown, suggesting potential applications in imaging, therapy and cosmetics fields.
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Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern.
Tatiana Segura,Brian C. Anderson,Peter Chung,Rebecca E. Webber,Kenneth R. Shull,Lonnie D. Shea +5 more
TL;DR: A crosslinking strategy targeting the alcohol groups via a poly(ethylene glycol) diepoxide crosslinker was investigated for the generation of degradable HA hydrogels, which could be functionalized with the biomolecule neutravidin by incorporation of biotin along the HA backbone.