D
Dong-Kug Choi
Researcher at Konkuk University
Publications - 195
Citations - 11563
Dong-Kug Choi is an academic researcher from Konkuk University. The author has contributed to research in topics: Neuroinflammation & Microglia. The author has an hindex of 48, co-authored 183 publications receiving 9927 citations. Previous affiliations of Dong-Kug Choi include Kyungpook National University & Columbia University.
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G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits.
TL;DR: GPCRs’ role in the pathophysiology of different neurodegenerative disease progressions and cognitive deficits has been highlighted, and an emphasis has been placed on the current pharmacological developments with GPCRs to provide an insight into a potential therapeutic target in the treatment of Neurodegeneration.
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Protective effect of Chrysanthemum indicum Linne against 1-methyl-4-phenylpridinium ion and lipopolysaccharide-induced cytotoxicity in cellular model of Parkinson's disease.
TL;DR: The present investigation scientifically supports the long history and safe usage of CI as an important functional food with potential benefits in ameliorating deleterious conditions seen in PD.
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Chrysanthemum morifolium Ramat (CM) extract protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
In Su Kim,Sushruta Koppula,Pyo-Jam Park,Ee Hwa Kim,Chan Gil Kim,Wahn Soo Choi,Kwang-Ho Lee,Dong-Kug Choi +7 more
TL;DR: It is demonstrated that Chrysanthemum morifolium possesses potent neuroprotective activity and therefore, might be a potential candidate in neurodegenerative diseases such as Parkinson's disease.
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Cuminum cyminum extract attenuates scopolamine-induced memory loss and stress-induced urinary biochemical changes in rats: a noninvasive biochemical approach.
Sushruta Koppula,Dong-Kug Choi +1 more
TL;DR: This study provides scientific support for the antistress, antioxidant, and memory-enhancing activities of cumin extract and substantiates that its traditional use as a culinary spice in foods is beneficial and scientific in combating stress and related disorders.
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Dual Functionality of Myeloperoxidase in Rotenone-Exposed Brain-Resident Immune Cells
Chi Young Chang,Mi Jeon Song,Sae Bom Jeon,Hee Jung Yoon,Dae Kee Lee,In Hoo Kim,Kyungho Suk,Dong-Kug Choi,Eun Jung Park +8 more
TL;DR: It is shown that microglia, unlike neurons, do not undergo death; instead, they exhibit distinctive activated properties under rotenone-exposed conditions, playing a critical regulatory role in modulating pathological and protective events in the brain.