D
Dorothy V. Reimert
Researcher at Johns Hopkins University School of Medicine
Publications - 3
Citations - 1248
Dorothy V. Reimert is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Semaphorin & Neuropilins. The author has an hindex of 3, co-authored 3 publications receiving 1179 citations.
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Journal ArticleDOI
Neuropilin-1 Conveys Semaphorin and VEGF Signaling during Neural and Cardiovascular Development
Chenghua Gu,E. Rene Rodriguez,Dorothy V. Reimert,Tianzhi Shu,Bernd Fritzsch,Linda J. Richards,Alex L. Kolodkin,David D. Ginty +7 more
TL;DR: Npn-1 is a multifunctional receptor that mediates the activities of structurally distinct ligands during development of the heart, vasculature, and nervous system and shows that VEGF-NPN-1 signaling in endothelial cells is required for angiogenesis.
Journal ArticleDOI
Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.
Chenghua Gu,Yutaka Yoshida,Jean Livet,Dorothy V. Reimert,Fanny Mann,Janna Merte,Christopher E. Henderson,Thomas M. Jessell,Alex L. Kolodkin,David D. Ginty +9 more
TL;DR: It is found that signaling by semaphorin 3E (Sema3E) and its receptor plexin-D1 controls endothelial cell positioning and the patterning of the developing vasculature in the mouse.
Journal ArticleDOI
Linx mediates interaxonal interactions and formation of the internal capsule.
TL;DR: It is shown that the transmembrane protein Linx is robustly expressed in the prethalamus and lateral ganglionic eminence-derived corridor and on corticofugal axons, but not on thalamocortical axon, and that mice with a null mutation of Linx exhibit a complete absence of the IC.