D
Dustin L. Dillon
Researcher at University of California, Los Angeles
Publications - 5
Citations - 76
Dustin L. Dillon is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Pancreatitis & Autophagy. The author has an hindex of 2, co-authored 5 publications receiving 27 citations.
Papers
More filters
Journal ArticleDOI
Transgenic expression of GFP-LC3 perturbs autophagy in exocrine pancreas and acute pancreatitis responses in mice
Olga A. Mareninova,Wenzhuo Jia,Sophie Gretler,Conner L. Holthaus,Diana D. H. Thomas,Michael Pimienta,Dustin L. Dillon,Anna S. Gukovskaya,Ilya Gukovsky,Guy E. Groblewski +9 more
TL;DR: GFP-LC3 expression affected key pancreatitis responses; most dramatically, it worsened increases in serum AMY (amylase), a diagnostic marker of acute pancreatitis, in several mouse models, and indicates that application of GFP- LC3 mice in disease models should be done with caution.
Journal ArticleDOI
Mast cell infiltration associated with loss of interstitial cells of Cajal and neuronal degeneration in achalasia.
Zuqiang Liu,Wei-Feng Chen,Yun Wang,Xiao-Yue Xu,Yi‐Gang Zeng,Dustin L. Dillon,Jing Cheng,Mei-Dong Xu,Yun-Shi Zhong,Yi-Qun Zhang,Li-Qing Yao,Ping-Hong Zhou,Quan-Lin Li +12 more
TL;DR: This study was designed to explore the role of mast cells in achalasia and supported the hypothesis that autoimmune‐mediated inflammatory responses produce inhibitory neuronal degeneration.
Journal ArticleDOI
Dysregulation of mannose-6-phosphate–dependent cholesterol homeostasis in acinar cells mediates pancreatitis
Olga A. Mareninova,Eszter T. Vegh,Natalia Shalbueva,Carli J. Wightman,Dustin L. Dillon,Sudarshan R. Malla,Yan Xie,Toshimasa Takahashi,Zoltán Rakonczay,Samuel W. French,Herbert Y. Gaisano,Fred S. Gorelick,Stephen J. Pandol,Steven J. Bensinger,Nicholas O. Davidson,David W. Dawson,Ilya Gukovsky,Anna S. Gukovskaya +17 more
TL;DR: In this article, the mannose-6-phosphate (M6P) pathway of hydrolase delivery to lysosomes critically regulates pancreatic acinar cell cholesterol metabolism.
Journal ArticleDOI
The obesity paradox: Underweight patients are at the greatest risk of mortality after cholecystectomy
Sarah E. Rudasill,Dustin L. Dillon,Krystal Karunungan,Alexandra L. Mardock,Joseph Hadaya,Yas Sanaiha,Zachary Tran,Peyman Benharash +7 more
TL;DR: In this article, the association of body mass index with morbidity, mortality, and resource use after cholecystectomy was examined for adults undergoing open and laparoscopic surgery.
Journal ArticleDOI
Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis.
Olga A. Mareninova,Dustin L. Dillon,Carli J. Wightman,Iskandar Yakubov,Toshimasa Takahashi,Herbert Y. Gaisano,Keith Munson,Masaki Ohmuraya,David W. Dawson,Ilya Gukovsky,Anna S. Gukovskaya +10 more
TL;DR: In this article, the role of Rab9 in pancreatic autophagy and pancreatitis severity was examined in transgenic mice with and without Rab9 overexpression and adenoviral transduction of acinar cells and showed that Rab9 decrease in experimental and human pancreatitis is a protective response to sustain canonical autophy and alleviate disease severity.