E
Eduard Ling
Researcher at Ben-Gurion University of the Negev
Publications - 29
Citations - 1108
Eduard Ling is an academic researcher from Ben-Gurion University of the Negev. The author has contributed to research in topics: Streptococcus pneumoniae & Internal medicine. The author has an hindex of 11, co-authored 23 publications receiving 940 citations.
Papers
More filters
Journal ArticleDOI
Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy
Paulina Navon Elkan,Sarah B. Pierce,Reeval Segel,Reeval Segel,Tom Walsh,Judith Barash,Shai Padeh,Abraham Zlotogorski,Yackov Berkun,Joseph J. Press,Mukamel M,Isabel Voth,Philip J. Hashkes,Liora Harel,Vered Hoffer,Eduard Ling,Fatoş Yalçınkaya,Ozgur Kasapcopur,Ming K. Lee,Rachel E. Klevit,Paul Renbaum,Ariella Weinberg-Shukron,Ariella Weinberg-Shukron,Elif Funda Sener,Elif Funda Sener,Barbara Schormair,Sharon Zeligson,Dina Marek-Yagel,Tim M. Strom,Mordechai Shohat,Mordechai Shohat,Amihood Singer,Alan Rubinow,Elon Pras,Juliane Winkelmann,Juliane Winkelmann,Mustafa Tekin,Yair Anikster,Mary Claire King,Ephrat Levy-Lahad,Ephrat Levy-Lahad +40 more
TL;DR: Recessive loss-of-function mutations of ADA2, a growth factor that is the major extracellular adenosine deaminase, can cause polyarteritis nodosa vasculopathy with highly varied clinical expression.
Journal ArticleDOI
Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse
Eduard Ling,Galia Feldman,Maxim Portnoi,Ron Dagan,Karin Overweg,Francis Mulholland,Vered Chalifa-Caspi,Jerry M. Wells,Yaffa Mizrachi-Nebenzahl +8 more
TL;DR: The immunoproteomics based approach utilized in the present study appears to be a suitable tool for identification of novel S. pneumoniae vaccine candidates.
Journal ArticleDOI
Contribution of IL-1 to resistance to Streptococcus pneumoniae infection.
Daniel Kafka,Eduard Ling,Galia Feldman,Daniel Benharroch,Elena Voronov,Noga Givon-Lavi,Yoichiro Iwakura,Ron Dagan,Ron N. Apte,Yaffa Mizrachi-Nebenzahl +9 more
TL;DR: All three isoforms contribute to protection against S. pneumoniae; the results suggest that IL-1beta has a major role in resistance to primary pneumococcal infection while the role ofIL-1alpha is less important.
Journal ArticleDOI
Virulence of Streptococcus pneumoniae may be determined independently of capsular polysaccharide.
Y. Mizrachi Nebenzahl,Nurith Porat,S. Lifshitz,S. Novick,A. Levi,Eduard Ling,O. Liron,Shaul Mordechai,Ranjit Sahu,Ron Dagan +9 more
TL;DR: It is concluded that factor(s) in addition to the capsule, contribute to disease outcome in mice inoculated intranasally with Streptococcus pneumoniae isolates of serotype 14 and a capsular switch of 14R, strain 9VR.
Journal ArticleDOI
Pneumococcal 6-phosphogluconate-dehydrogenase, a putative adhesin, induces protective immune response in mice.
D. Daniely,Maxim Portnoi,Marilou Shagan,Angel Porgador,Noga Givon-Lavi,Eduard Ling,Ron Dagan,Y. Mizrachi Nebenzahl +7 more
TL;DR: 6PGD was identified as a surface‐located immunogenic lectin protein capable of acting as an adhesin and its importance to bacterial pathogenesis was demonstrated by the ability of r6 PGD to elicit a protective immune response in mice.