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Elif Funda Sener
Researcher at Erciyes University
Publications - 55
Citations - 980
Elif Funda Sener is an academic researcher from Erciyes University. The author has contributed to research in topics: Autism & Medicine. The author has an hindex of 11, co-authored 45 publications receiving 702 citations. Previous affiliations of Elif Funda Sener include John P. Hussman Institute for Human Genomics & University of Miami.
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Journal ArticleDOI
Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy
Paulina Navon Elkan,Sarah B. Pierce,Reeval Segel,Reeval Segel,Tom Walsh,Judith Barash,Shai Padeh,Abraham Zlotogorski,Yackov Berkun,Joseph J. Press,Mukamel M,Isabel Voth,Philip J. Hashkes,Liora Harel,Vered Hoffer,Eduard Ling,Fatoş Yalçınkaya,Ozgur Kasapcopur,Ming K. Lee,Rachel E. Klevit,Paul Renbaum,Ariella Weinberg-Shukron,Ariella Weinberg-Shukron,Elif Funda Sener,Elif Funda Sener,Barbara Schormair,Sharon Zeligson,Dina Marek-Yagel,Tim M. Strom,Mordechai Shohat,Mordechai Shohat,Amihood Singer,Alan Rubinow,Elon Pras,Juliane Winkelmann,Juliane Winkelmann,Mustafa Tekin,Yair Anikster,Mary Claire King,Ephrat Levy-Lahad,Ephrat Levy-Lahad +40 more
TL;DR: Recessive loss-of-function mutations of ADA2, a growth factor that is the major extracellular adenosine deaminase, can cause polyarteritis nodosa vasculopathy with highly varied clinical expression.
Journal ArticleDOI
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/ Src signaling in triple negative breast cancer cells
Zuhal Hamurcu,Nesrin Delibaşı,Seda Geçene,Elif Funda Sener,Hamiyet Donmez-Altuntas,Yusuf Ozkul,Halit Canatan,Bulent Ozpolat +7 more
TL;DR: It is suggested that LC3 and Beclin-1 are required for cell proliferation, survival, migration and invasion, and may contribute to tumor growth and progression of highly aggressive and metastatic TNBC cells and therapeutic targeting of autophagy genes may be a potential therapeutic strategy for TNBC in breast cancer.
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MTHFR Gene C677T Polymorphism in Autism Spectrum Disorders
TL;DR: It is concluded that other MTHFR polymorphisms such as A1298C or other folate/homocysteine pathway genes may be studied to show their possible role in autism.
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FOXM1 plays a role in autophagy by transcriptionally regulating Beclin-1 and LC3 genes in human triple-negative breast cancer cells.
Zuhal Hamurcu,Zuhal Hamurcu,Nesrin Delibaşı,Ufuk Nalbantoglu,Elif Funda Sener,Nursultan Nurdinov,Bayram Tascı,Serpil Taheri,Yusuf Ozkul,Hamiyet Donmez-Altuntas,Halit Canatan,Bulent Ozpolat +11 more
TL;DR: The role of FOXM1 in the regulation of autophagy that plays a role in TNBC progression is examined and it is found thatFoxM1 is upregulated during induction of autophileagy, providing novel insight into the role of FoxM1 regulation of the autophagic survival pathway.
Journal ArticleDOI
A heritable profile of six miRNAs in autistic patients and mouse models.
Yusuf Ozkul,Serpil Taheri,Kezban Korkmaz Bayram,Elif Funda Sener,Ecmel Mehmetbeyoglu,Didem Behice Öztop,Fatma Aybuga,Esra Tufan,Arslan Bayram,Nazan Dolu,Gokmen Zararsiz,Leila Kianmehr,Feyzullah Beyaz,Züleyha Doğanyiğit,François Cuzin,Minoo Rassoulzadegan,Minoo Rassoulzadegan +16 more
TL;DR: A comparative analysis of the micro RNAs expressed in the serum of human ASD patients revealed that six microRNAs were expressed at low to very low levels compared to those in healthy controls, a starting point for evaluating the changes in the activity of the target genes and the underlying mechanism(s).