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Edward H. Birkenmeier

Researcher at Saint Louis University

Publications -  50
Citations -  5648

Edward H. Birkenmeier is an academic researcher from Saint Louis University. The author has contributed to research in topics: Mucopolysaccharidosis & Mucopolysaccharidosis VII. The author has an hindex of 34, co-authored 50 publications receiving 5537 citations.

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Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

TL;DR: Observations raise the possibility that the synthesis of C/EBP may be responsive to humoral factors and that modulation in C/ EBP expression might mediate coordinated changes in gene expression that facilitate adaptive challenges met during development or during the fluctuating physiological states of adult life.
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Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

TL;DR: Large quantities of DNA from most tissues of each animal are prepared to create a community resource of interspecific backcross DNA for use by laboratories interested in mapping loci in the mouse.
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CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

TL;DR: Data represent a direct demonstration that T cells reactive with conventional antigens of the enteric bacterial flora can mediate chronic inflammatory bowel disease.
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Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis

TL;DR: Major differences in genetic susceptibility to DSS-induced colitis among inbred strains of mice are demonstrated and knowledge of these strain differences in Genetic responsiveness to acute inflammatory stress in the large intestine will permit design of genetic crosses to elucidate the genes involved.
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Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.

TL;DR: Surprisingly, a sensitive S1 nuclease assay indicated that the relative level of kidney gusmps mRNA responded normally to androgen induction by increasing approximately 11-fold, and may offer valuable information on the pathogenesis of human MPS VII.