M
Minoru S.H. Ko
Researcher at Keio University
Publications - 191
Citations - 16754
Minoru S.H. Ko is an academic researcher from Keio University. The author has contributed to research in topics: Embryonic stem cell & Gene. The author has an hindex of 62, co-authored 186 publications receiving 15543 citations. Previous affiliations of Minoru S.H. Ko include Johns Hopkins University & Government of the United States of America.
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Journal ArticleDOI
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Shinji Masui,Yuhki Nakatake,Yayoi Toyooka,Daisuke Shimosato,Rika Yagi,Kazue Takahashi,Hitoshi Okochi,Akihiko Okuda,Ryo Matoba,Alexei A. Sharov,Minoru S.H. Ko,Hitoshi Niwa +11 more
TL;DR: The results indicate that the essential function of Sox2 is to stabilize ES cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression.
Journal ArticleDOI
Dynamics of Global Gene Expression Changes during Mouse Preimplantation Development
TL;DR: A cascade of gene activation from maternal RNA/protein sets to zygotic genome activation and thence to MGA gene sets is proposed, which is a first step toward analysis of the complex gene regulatory networks.
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The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC)
Daniela S. Gerhard,Lukas Wagner,Elise A. Feingold,Carolyn M. Shenmen,Lynette H. Grouse,Greg Schuler,Steven L. Klein,Susan Old,Rebekah S. Rasooly,Peter J. Good,Mark S. Guyer,Allison M. Peck,Jeffery G. Derge,David J. Lipman,Francis S. Collins,Wonhee Jang,Steven Sherry,Mike Feolo,Leonie Misquitta,Eduardo Lee,Kirill Rotmistrovsky,Susan F. Greenhut,Carl F. Schaefer,Kenneth H. Buetow,Tom I. Bonner,David Haussler,Jim Kent,Mark Diekhans,Terry Furey,Michael R. Brent,Christa Prange,Kirsten Schreiber,Nicole Shapiro,Narayan K. Bhat,Ralph F. Hopkins,Florence Hsie,Tom Driscoll,M. Bento Soares,Maria de Fatima Bonaldo,Thomas L. Casavant,Todd E. Scheetz,Michael J. Brownstein,Ted B. Usdin,Shiraki Toshiyuki,Piero Carninci,Yulan Piao,Dawood B. Dudekula,Minoru S.H. Ko,Koichi Kawakami,Yutaka Suzuki,Sumio Sugano,C. E. Gruber,M. R. Smith,Blake A. Simmons,Troy Moore,Richard C. Waterman,Stephen L. Johnson,Yijun Ruan,Chia-Lin Wei,Sinnakaruppan Mathavan,Preethi H. Gunaratne,Jia Qian Wu,Angela M. Garcia,Stephen W. Hulyk,Edwin Fuh,Ye Yuan,Anna Sneed,Carla Kowis,Anne Hodgson,Donna M. Muzny,John Douglas Mcpherson,Richard A. Gibbs,Jessica Fahey,Jessica Fahey,Erin Helton,Mark Ketteman,Anuradha Madan,Anuradha Madan,Stephanie Rodrigues,Stephanie Rodrigues,Amy Sanchez,Michelle Whiting,Anup Madan,Anup Madan,Alice C. Young,Keith Wetherby,Steven J. Granite,Peggy N. Kwong,Charles P. Brinkley,Russell L. Pearson,Gerard G. Bouffard,Robert W. Blakesly,Eric D. Green,Mark Dickson,Alex Rodriguez,Jane Grimwood,Jeremy Schmutz,Richard M. Myers,Yaron S.N. Butterfield,Malachi Griffith,Obi L. Griffith,Martin Krzywinski,Nancy Y. Liao,Ryan Morrin,Diana L. Palmquist,Anca Petrescu,Ursula Skalska,Duane E. Smailus,Jeff M. Stott,Angelique Schnerch,Jacqueline E. Schein,Steven J.M. Jones,Robert A. Holt,Agnes Baross,Marco A. Marra,Sandra W. Clifton,Kathryn A. Makowski,Stephanie Bosak,Joel A. Malek +118 more
TL;DR: Comparison of the sequence of the MGC clones to reference genome sequences reveals that most cDNA clones are of very high sequence quality, although it is likely that some cDNAs may carry missense variants as a consequence of experimental artifact, such as PCR, cloning, or reverse transcriptase errors.
Journal ArticleDOI
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource
Lucy B. Rowe,J. H. Nadeau,R. Turner,Wayne N. Frankel,Verity A. Letts,Janan Eppig,Minoru S.H. Ko,S. J. Thurston,Edward H. Birkenmeier +8 more
TL;DR: Large quantities of DNA from most tissues of each animal are prepared to create a community resource of interspecific backcross DNA for use by laboratories interested in mapping loci in the mouse.
Journal ArticleDOI
Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells
Lioudmila V. Sharova,Alexei A. Sharov,Timur Nedorezov,Yulan Piao,Nabeebi Shaik,Minoru S.H. Ko +5 more
TL;DR: The mRNA decay rates presented in this report are the largest data set for mammals and the first for ES cells and the stability of mRNAs correlated more significantly with the structural features of genes than the function of genes.