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Eeva-Liisa Eskelinen
Researcher at University of Turku
Publications - 136
Citations - 32990
Eeva-Liisa Eskelinen is an academic researcher from University of Turku. The author has contributed to research in topics: Autophagy & Endosome. The author has an hindex of 60, co-authored 124 publications receiving 28293 citations. Previous affiliations of Eeva-Liisa Eskelinen include Dalhousie University & University of Kiel.
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Seeing is believing: The impact of electron microscopy on autophagy research
TL;DR: The impact that electron microscopy has had on autophagy research since the discovery of this self-degradation process in the mid-1950s is summarized.
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LAMP-2: a control step for phagosome and autophagosome maturation
TL;DR: Recent studies in LAMP double-knockout fibroblasts suggests that LAMP-deficiency impairs the dynein-mediated transport of lysosomes to perinuclear regions where fusion with (auto)phagosomes occurs.
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Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes
Roswitha Krick,Y Muehe,Tanja Prick,Sebastian C B Bremer,Petra Schlotterhose,Eeva-Liisa Eskelinen,Jonathan I. Millen,David S. Goldfarb,Michael Thumm +8 more
TL;DR: It is concluded that a spectrum of ATG genes is required for the terminal vacuole enclosure and fusion stages of PMN, and PMN does not require the complete vacuoles homotypic fusion genes.
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Aut5/Cvt17p, a Putative Lipase Essential for Disintegration of Autophagic Bodies inside the Vacuole
TL;DR: Characteristic missorting in vps class E and fab1Delta cells, which affects the multivesicular body (MVB) pathway, suggests vacuolar targeting of Aut5-Ha similar to that of the MVB pathway, and pulse-chase experiments clearly indicated that autophagic-body degradation with 50 to 70 min of half-life is dependent on vacUolar proteinase A.
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The dual role of autophagy in cancer.
TL;DR: In conclusion, the FK506-binding protein 51 plays a role in the autophagy-linked radiation resistance of malignant melanoma and should be considered a target for further research.