Eileen T. Nakano

TL;DR: Results support the development of a dengue virus tetravalent vaccine based on the four 80E subunits produced in the Drosophila S2 cell expression system, which are highly immunogenic and capable of eliciting protective responses in both mice and monkeys.

TL;DR: The filamentous fungi, owing to their ability to secrete high levels of proteins, are attractive organisms for the expression and secretion of heterologous proteins of commercial and medical value and their utility by expression of a bovine preprochymosin cDNA and secrete of processed, enzymatically active bovinesin is reported.

TL;DR: The truncated HCV E2 polypepides lack the HVR1 region that provides immune protection against HCV as mentioned in this paper, and the present invention also provides immunogenic compositions of such polypeptides and the methods of use thereof.

TL;DR: De-identified/anonymized medical waste with clinical history of SARS-CoV-2 natural infection, with no associated clinicoepidemiological data were available.

TL;DR: In this article , an algorithm for monitoring the evolution of SARS-CoV-2 in the context of vaccines and monoclonal antibodies is presented. But the algorithm is based on the patterns of amino acid substitutions elucidated, which can be harnessed in designing vaccines with relevant immunogenic epitopes.