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Eliana Martins Lima
Researcher at Universidade Federal de Goiás
Publications - 131
Citations - 3153
Eliana Martins Lima is an academic researcher from Universidade Federal de Goiás. The author has contributed to research in topics: Liposome & Medicine. The author has an hindex of 25, co-authored 120 publications receiving 2356 citations. Previous affiliations of Eliana Martins Lima include University of Brasília & University of Pennsylvania.
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Journal ArticleDOI
Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
Nicolas Bertrand,Nicolas Bertrand,Philippe Grenier,Morteza Mahmoudi,Eliana Martins Lima,Eliana Martins Lima,Eric A. Appel,Eric A. Appel,Flavio Dormont,Jong-Min Lim,Jong-Min Lim,Rohit Karnik,Robert Langer,Omid C. Farokhzad,Omid C. Farokhzad +14 more
TL;DR: Light is shed on the essential role of the surface and other physicochemical properties of a library of nanoparticles on their in vivo pharmacokinetics and how physicochemical characteristics influence blood circulation and early distribution.
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Micelles of Different Morphologies—Advantages of Worm-like Filomicelles of PEO-PCL in Paclitaxel Delivery
TL;DR: PEO–PCL based worm-like filomicelles appear to be promising pharmaceutical nanocarriers with improved solubilization efficiency and comparable stability to spherical micelles, as well as better safety and efficacy in vitro compared to the prevalent Cremophor® EL TAX formulation.
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Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged release
Leonardo Gomes Souza,Emmanuelle de Jesus Silva,André Martins,Mariana Flavia da Mota,Rodolpho C. Braga,Eliana Martins Lima,Marize Campos Valadares,Stephânia Fleury Taveira,Ricardo Neves Marreto +8 more
TL;DR: Developing, for the first time, solid lipid nanoparticles and nanostructured lipid carriers (NLC) with a high drug loading for topotecan and Surprisingly, there were no significant differences between the NLCs and SLNs, and both are potential carriers for topOTecan delivery.
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Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil
TL;DR: Preliminary in vivo experiments suggest that treatment with photocleavable nanoparticles can significantly reduce the teratogenicity of bisphenol A, triclosan and 17α-ethinyl estradiol without generating obviously toxic byproducts.
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Anti-polyethylene glycol antibodies alter the protein corona deposited on nanoparticles and the physiological pathways regulating their fate in vivo.
TL;DR: It is shown that the anti‐PEG Immunoglobulin M (IgM) raised in mice following the injection of polymeric nanoparticles could have significant neutralizing effects on subsequent doses of PEGylated nanosystems in vivo.