E
Elijah Mak
Researcher at University of Cambridge
Publications - 89
Citations - 3062
Elijah Mak is an academic researcher from University of Cambridge. The author has contributed to research in topics: Dementia & Dementia with Lewy bodies. The author has an hindex of 28, co-authored 75 publications receiving 2009 citations. Previous affiliations of Elijah Mak include State University of New York System.
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Journal ArticleDOI
18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy.
Luca Passamonti,Patricia Vázquez Rodríguez,Young T. Hong,Kieren Allinson,David Williamson,Robin J Borchert,Saber Sami,Thomas E. Cope,W Richard Bevan-Jones,P. Simon Jones,Robert Arnold,Ajenthan Surendranathan,Elijah Mak,Li Su,Tim D. Fryer,Franklin I. Aigbirhio,John T. O'Brien,James B. Rowe +17 more
TL;DR: By comparing patients with Alzheimer’s disease and progressive supranuclear palsy, Passamonti et al. show that [18F]AV-1451 displays greater specificity for Alzheimer-related tau pathology than PSP-related pathology.
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Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis
Chris Stinton,Ian G. McKeith,John-Paul Taylor,Louise Lafortune,Eneida Mioshi,Elijah Mak,Victoria C. Cambridge,James Mason,Alan J. Thomas,John T. O'Brien +9 more
TL;DR: High-level evidence related to pharmacological strategies for managing Lewy body dementia is rare and strategies for important areas of need, such as autonomic symptoms and caregiver burden, have not been investigated.
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Baseline and longitudinal grey matter changes in newly diagnosed Parkinson’s disease: ICICLE-PD study
Elijah Mak,Li Su,Guy B. Williams,Michael J. Firbank,Rachael A Lawson,Alison J. Yarnall,Gordon W Duncan,Adrian M. Owen,Tien K. Khoo,David J. Brooks,David J. Brooks,James B. Rowe,James B. Rowe,Roger A. Barker,David J. Burn,John T. O'Brien +15 more
TL;DR: Patients with PDMCI show accelerated cortical thinning compared to non-cognitively impaired patients and healthy controls, which may constitute biomarkers for increased dementia risk.
Journal ArticleDOI
Inflammation and cerebral small vessel disease: A systematic review.
TL;DR: Regional analysis revealed that systemic and vascular inflammation were differentially related to two distinct forms of SVD, suggesting the potential utility of treatments targeting the brain endothelium and blood brain barrier to combat SVD and associated neurodegenerative diseases.
Journal ArticleDOI
Neuroinflammation and Functional Connectivity in Alzheimer's Disease: Interactive Influences on Cognitive Performance
Luca Passamonti,Kamen A. Tsvetanov,P.S. Jones,William Richard Bevan-Jones,Robert Arnold,Robin J Borchert,Elijah Mak,Li Su,John T. O'Brien,James B. Rowe +9 more
TL;DR: It is provided clear evidence that in vivo neuroinflammation in AD impairs large-scale network connectivity; and that the link between neuro inflammation and functional network connectivity is relevant to cognitive impairment.