E
Elliott M. Antman
Researcher at Brigham and Women's Hospital
Publications - 738
Citations - 187175
Elliott M. Antman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 161, co-authored 716 publications receiving 179462 citations. Previous affiliations of Elliott M. Antman include Duke University & Katholieke Universiteit Leuven.
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Assessment of the efficacy and safety of antiarrhythmic therapy for chronic atrial fibrillation: Observations on the role of trial design and implications of drug-related mortality
TL;DR: Compared to findings in the randomized control trials, the magnitude of the treatment benefit in nonrandomized trials was smaller and declined markedly over time, and the percentage of patients remaining in sinus rhythm in the uncontrolled trials was intermediate to the percentages in the other two trial designs.
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Risk factors for the development of recurrent atrial fibrillation: Role of pacing and clinical variables
TL;DR: Patients with recurrent symptomatic chronic or paroxysmal atrial fibrillation for which conventional antiarrhythmic agents had failed were treated with propafenone or sotalol, and dual-chamber pacing improved maintenance of sinus rhythm.
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Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44.
Andrew L. Frelinger,Alan D. Michelson,Stephen D. Wiviott,Dietmar Trenk,Franz-Josef Neumann,Debra L. Miller,Joseph A. Jakubowski,Timothy M. Costigan,Carolyn H. McCabe,Elliott M. Antman,Eugene Braunwald +10 more
TL;DR: A patient's intrinsic platelet response to ADP before exposure to thienopyridines contributes to residual platelet reactivity to adenosine diphosphate despite high level P2Y12 blockade with high-dose clopidogrel or even higher level P 2Y 12 blockade with prasugrel.
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Troponin measurements in ischemic heart disease: more than just a black and white picture.
TL;DR: In this article, the authors categorize patients with ischemic discomfort into those who present with ST elevation on the 12-lead electrocardiogram (ECG) versus those who do not present with stent elevation.
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Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine
TL;DR: The tenets of adaptive clinical trial design as they may apply to an era of expanding knowledge of systems pharmacology and pharmacogenomics, and clinical trail design in network medicine are reviewed.