E
Emeline Houël
Researcher at University of the French West Indies and Guiana
Publications - 35
Citations - 606
Emeline Houël is an academic researcher from University of the French West Indies and Guiana. The author has contributed to research in topics: Quassia amara & Quassinoid. The author has an hindex of 13, co-authored 31 publications receiving 487 citations. Previous affiliations of Emeline Houël include Agro ParisTech & Centre national de la recherche scientifique.
Papers
More filters
Journal ArticleDOI
Antimalarial Activity of Simalikalactone E, a New Quassinoid from Quassia amara L. (Simaroubaceae)
N. Cachet,N. Cachet,Franciane Ho-A-Kwie,Franciane Ho-A-Kwie,Stéphanie Bertani,Geneviève Bourdy,Geneviève Bourdy,Eric Deharo,Eric Deharo,Didier Stien,Emeline Houël,Heinz Gornitzka,Judith Fillaux,Séverine Chevalley,Séverine Chevalley,Alexis Valentin,Alexis Valentin,Valérie Jullian,Valérie Jullian +18 more
TL;DR: The isolation and identification of a new quassinoid named simalikalactone E (SkE), extracted from a widely used Amazonian antimalarial remedy made out of Quassia amara L. (Simaroubaceae) leaves, and its cytotoxicity on mammalian cells was dependent on the cell line, displaying a good selectivity index when tested on nontumorogenic cells.
Journal ArticleDOI
Diversity of the volatile organic compounds emitted by 55 species of tropical trees: a survey in French Guiana.
Elodie A. Courtois,Timothy Charles Eliot Paine,Pierre-Alain Blandinières,Didier Stien,Jean-Marie Bessière,Emeline Houël,Christopher Baraloto,Jérôme Chave +7 more
TL;DR: A survey of the VOCs released immediately after mechanical damage of the bark and the leaves of 195 individual trees belonging to 55 tropical tree species in a lowland rainforest of French Guiana discovered a remarkably high chemical diversity, with 264 distinct V OCs and a mean of 37 compounds per species.
Journal ArticleDOI
Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity.
Emeline Houël,Stéphane Bertani,Geneviève Bourdy,Geneviève Bourdy,Eric Deharo,Eric Deharo,Valérie Jullian,Valérie Jullian,Alexis Valentin,Alexis Valentin,Séverine Chevalley,Séverine Chevalley,Didier Stien +12 more
TL;DR: This preparation should not be recommended for treatment of malaria until a clinical study in humans is performed with SkD, and both biological activity and cytotoxicity of the remedy may be attributed solely to the presence of SkD.
Journal ArticleDOI
Simalikalactone D is responsible for the antimalarial properties of an Amazonian traditional remedy made with Quassia amara L. (Simaroubaceae).
Stéphane Bertani,Emeline Houël,Didier Stien,Lionel Chevolot,Valérie Jullian,Giovanni Garavito,Geneviève Bourdy,Eric Deharo +7 more
TL;DR: A known quassinoid, simalikalactone D (SkD), was identified as the active compound, with an IC(50) value of 10nM against FcB1 Plasmodium falciparum chloroquine resistant strain in vitro and in vivo, and these findings confirm the traditional use of this herbal tea.
Journal ArticleDOI
Differences in volatile terpene composition between the bark and leaves of tropical tree species
Elodie A. Courtois,Elodie A. Courtois,Christopher Baraloto,C. E. Timothy Paine,Pascal Petronelli,Pierre-Alain Blandinières,Didier Stien,Emeline Houël,Jean-Marie Bessière,Jérôme Chave +9 more
TL;DR: It is found that the mixture of volatile terpenes released by bark is different and more diverse than that released by leaves, both in monoterpenes and sesquiterpenes, which supports the hypothesis that in woody plants, the outermost part of the trunk should hold a more diverse blend of volatileTerpenes.