E
Emi Yoshigai
Researcher at Ritsumeikan University
Publications - 18
Citations - 469
Emi Yoshigai is an academic researcher from Ritsumeikan University. The author has contributed to research in topics: Nitric oxide synthase & Antisense RNA. The author has an hindex of 13, co-authored 16 publications receiving 398 citations. Previous affiliations of Emi Yoshigai include Kyushu University.
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Journal ArticleDOI
The anti-inflammatory effects of flavanol-rich lychee fruit extract in rat hepatocytes.
Ryota Yamanishi,Emi Yoshigai,Tetsuya Okuyama,Masatoshi Mori,Hiromitsu Murase,Toru Machida,Tadayoshi Okumura,Mikio Nishizawa +7 more
TL;DR: The results suggest that flavanols may be responsible for the anti-inflammatory and hepatoprotective effects of FRLFE and may be used to treat inflammatory diseases.
Journal ArticleDOI
Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1β-treated hepatocytes
Emi Yoshigai,Toru Machida,Tetsuya Okuyama,Masatoshi Mori,Hiromitsu Murase,Ryota Yamanishi,Tadayoshi Okumura,Tadayoshi Okumura,Yukinobu Ikeya,Hoyoku Nishino,Mikio Nishizawa +10 more
TL;DR: The suppression of iNOS induction by nobiletin suggests thatnobiletin may be responsible for the anti-inflammatory effects of citrus peels and have a therapeutic potential for liver diseases.
Journal ArticleDOI
Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPβ and NF-κB in rat hepatocytes
Yuna Takimoto,Hai-Yan Qian,Emi Yoshigai,Tadayoshi Okumura,Tadayoshi Okumura,Yukinobu Ikeya,Mikio Nishizawa +6 more
TL;DR: It is demonstrated that gomisin N and γ-schizandrin are involved in the hepatoprotective effect of the FSC extract, which has therapeutic potential for liver disease.
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Interleukin‐1β induces tumor necrosis factor‐α secretion from rat hepatocytes
Emi Yoshigai,Takafumi Hara,Hiroyuki Inaba,Iwao Hashimoto,Yoshito Tanaka,Masaki Kaibori,Tominori Kimura,Tadayoshi Okumura,Tadayoshi Okumura,A-Hon Kwon,Mikio Nishizawa +10 more
TL;DR: Tumor necrosis factor‐α is a pleiotropic cytokine involved in various inflammatory diseases and is thought to be from hepatic macrophages known as Kupffer cells, predominantly in response to bacterial lipopolysaccharide (LPS).
Journal ArticleDOI
Stabilization of human interferon-α1 mRNA by its antisense RNA.
Tominori Kimura,Shiwen Jiang,Mikio Nishizawa,Emi Yoshigai,Iwao Hashimoto,Masao Nishikawa,Tadayoshi Okumura,Tadayoshi Okumura,Hisao Yamada +8 more
TL;DR: It is shown that natural antisense (AS) RNA is an important modulator of interferon- α1 (IFN-α1) mRNA levels and suggests a reason for the large number of overlapping complementary transcripts with previously unknown function.