Emilie V. Brotherhood

TL;DR: Higher concentrations may reflect the intensity of the disease in FTD and are associated with more rapid atrophy of the frontal lobes and show wide variability within each clinical and genetic group.

TL;DR: Impaired interoceptive accuracy correlated with reduced daily-life emotional sensitivity across the patient cohort, and with atrophy of right insula, cingulate, and amygdala on voxel-based morphometry in the impaired semantic variant group, delineating a network previously shown to support interoception processing in the healthy brain.

TL;DR: Evidence that neural activity reflecting the encoding of emotionally neutral information in memory is reduced when neutral and emotional stimuli are intermixed during encoding is reported, which might be caused by an asymmetrical competition for attentional and working memory resources between emotional and neutral information.

TL;DR: The sequence in which cognitive deficits appear in two dementia syndromes is characterized in order to characterize the sequence of events leading to these deficits.

TL;DR: Impaired emotional mimesis may be a core mechanism of disordered emotional signal understanding and reactivity in frontotemporal dementia, with implications for the development of novel physiological biomarkers of socio-emotional dysfunction in these diseases.