J
Jennifer M. Nicholas
Researcher at University of London
Publications - 156
Citations - 5316
Jennifer M. Nicholas is an academic researcher from University of London. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 31, co-authored 131 publications receiving 3980 citations. Previous affiliations of Jennifer M. Nicholas include National University of Singapore & Imperial College Healthcare.
Papers
More filters
Journal ArticleDOI
Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery.
Derek J. Hausenloy,Luciano Candilio,Richard Evans,Cono Ariti,David P. Jenkins,Shyam Kolvekar,Rosemary Knight,Gudrun Kunst,Chris Laing,Jennifer M. Nicholas,John Pepper,Steven Robertson,Maria Xenou,Tim Clayton,Derek M. Yellon +14 more
TL;DR: Remote ischemic preconditioning did not improve clinical outcomes in patients undergoing elective on-pump CABG with or without valve surgery and there were no significant between-group differences in either adverse events or the secondary end points of perioperative myocardial injury.
Journal ArticleDOI
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D. Rohrer,Jennifer M. Nicholas,Jennifer M. Nicholas,David M. Cash,John C. van Swieten,Elise G.P. Dopper,Lize C. Jiskoot,Rick van Minkelen,Serge A.R.B. Rombouts,M. Jorge Cardoso,Shona Clegg,Miklos Espak,Simon Mead,David L. Thomas,Enrico De Vita,Mario Masellis,Sandra E. Black,Morris Freedman,Ron Keren,Bradley J. MacIntosh,Ekaterina Rogaeva,David F. Tang-Wai,Maria Carmela Tartaglia,Robert Laforce,Fabrizio Tagliavini,Pietro Tiraboschi,Veronica Redaelli,Sara Prioni,Marina Grisoli,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Andrea Arighi,Giorgio G. Fumagalli,James B. Rowe,Ian Coyle-Gilchrist,Caroline Graff,Caroline Graff,Marie Fallström,Vesna Jelic,Vesna Jelic,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Christin Andersson,Christin Andersson,Håkan Thonberg,Håkan Thonberg,Lena Lilius,Giovanni B. Frisoni,Giuliano Binetti,Michela Pievani,Martina Bocchetta,Luisa Benussi,Roberta Ghidoni,Elizabeth Finger,Sandro Sorbi,Benedetta Nacmias,Gemma Lombardi,Cristina Polito,Jason D. Warren,Sebastien Ourselin,Nick C. Fox,Martin N. Rossor +63 more
TL;DR: Structural imaging and cognitive changes can be identified 5-10 years before expected onset of symptoms in asymptomatic adults at risk of genetic frontotemporal dementia, which could help to define biomarkers that can stage presymPTomatic disease and track disease progression.
Journal ArticleDOI
Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial.
Jeremy Chataway,Nadine Schuerer,A Alsanousi,Dennis Chan,David G. MacManus,David G. MacManus,K Hunter,K Hunter,Val Anderson,Val Anderson,Charles R. M. Bangham,Shona Clegg,Casper Nielsen,Nick C. Fox,Nick C. Fox,David Wilkie,Jennifer M. Nicholas,Jennifer M. Nicholas,Jennifer M. Nicholas,Virginia L. Calder,John Greenwood,Chris Frost,Richard Nicholas,Richard Nicholas +23 more
TL;DR: High-dose simvastatin reduced the annualised rate of whole-brain atrophy compared with placebo, and was well tolerated and safe, which support the advancement of this treatment to phase 3 testing.
Journal ArticleDOI
Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia
Jonathan D. Rohrer,Ione O.C. Woollacott,Katrina M. Dick,Emilie V. Brotherhood,Elizabeth Gordon,Alexander D. Fellows,Jamie Toombs,Ronald Druyeh,M. Jorge Cardoso,Sebastien Ourselin,Jennifer M. Nicholas,Niklas Norgren,Simon Mead,Ulf Andreasson,Kaj Blennow,Jonathan M. Schott,Nick C. Fox,Jason D. Warren,Henrik Zetterberg +18 more
TL;DR: Higher concentrations may reflect the intensity of the disease in FTD and are associated with more rapid atrophy of the frontal lobes and show wide variability within each clinical and genetic group.
Journal ArticleDOI
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.
Derek J. Hausenloy,Rajesh K. Kharbanda,Ulla Kristine Møller,Manish Ramlall,Manish Ramlall,Jens Aarøe,Robert Butler,Heerajnarain Bulluck,Tim Clayton,Ali Dana,Matthew Dodd,Thomas Engstrøm,Richard Evans,Jens Flensted Lassen,Erika Frischknecht Christensen,José Manuel García-Ruiz,Diana A. Gorog,Diana A. Gorog,Jakob Hjort,Richard F Houghton,Borja Ibanez,Rosemary Knight,Freddy Lippert,Jacob Lønborg,Michael Maeng,Dejan Milasinovic,Ranjit More,Jennifer M. Nicholas,Lisette Okkels Jensen,Alexander Perkins,Nebojsa Radovanovic,Roby Rakhit,Jan Ravkilde,Alisdair D Ryding,Michael Schmidt,Ingunn Skogstad Riddervold,Henrik Toft Sørensen,Goran Stankovic,Madhusudhan Varma,Ian Webb,Christian Juhl Terkelsen,John P Greenwood,John P Greenwood,Derek M. Yellon,Hans Erik Bøtker,Anders Junker,Anne Kaltoft,Morten Madsen,Evald Høj Christiansen,Lars Jakobsen,Steen Carstensen,Steen Dalby Kristensen,Troels Thim,Karin Møller Pedersen,Mette Tidemand Korsgaard,Allan Iversen,Erik Jørgensen,Francis R. Joshi,Frants Pedersen,Hans-Henrik Tilsted,Karam Alzuhairi,Kari Saunamäki,Lene Holmvang,Ole Ahlehof,Rikke Sørensen,Steffen Helqvist,Bettina Løjmand Mark,Anton Boel Villadsen,Bent Raungaard,Leif Thuesen,Martin Kirk Christiansen,Philip Freeman,Svend Eggert Jensen,Charlotte Schmidt Skov,Ahmed Aziz,Henrik Steen Hansen,Julia Ellert,Karsten Tange Veien,Knud Erik Pedersen,Knud Nørregård Hansen,Ole Ahlehoff,Helle Cappelen,Daniel Wittrock,Poul Anders Hansen,Jens Peter Ankersen,Kim Witting Hedegaard,John Kempel,Henning Kaus,Dennis Erntgaard,Danny Mejsner Pedersen,Matthias Giebner,Troels Martin Hansen,Mina Radosavljevic-Radovanovic,Maja Prodanovic,Lidija Savic,Marijana Pejic,Dragan Matic,Ana Uscumlic,Ida Subotic,Ratko Lasica,Vladan Vukcevic,Alfonso Suárez,Beatriz Samaniego,César Morís,Eduardo Segovia,Ernesto Hernández,Iñigo Lozano,Isaac Pascual,Jose M. Vegas-Valle,José Rozado,Juan Rondan,Pablo Avanzas,Raquel del Valle,Remigio Padrón,Alfonso García-Castro,Amalia Arango,Ana B. Medina-Cameán,Ana I. Fente,Ana Muriel-Velasco,Ángeles Pomar-Amillo,César L. Roza,César M. Martínez-Fernández,Covadonga Buelga-Díaz,David Fernández-Gonzalo,Elena Fernández,Eloy Díaz-González,Eugenio Martinez-González,Fernando Iglesias-Llaca,Fernando M. Viribay,Francisco J. Fernández-Mallo,Francisco J. Hermosa,Ginés Martínez-Bastida,Javier Goitia-Martín,José L. Vega-Fernández,Jose M. Tresguerres,Juan A. Rodil-Díaz,Lara Villar-Fernández,Lucía Alberdi,Luis Abella-Ovalle,Manuel de la Roz,Marcos Fernández-Carral Fernández-Carral,María C. Naves,María C. Peláez,María D. Fuentes,María García-Alonso,María J. Villanueva,María S. Vinagrero,María Vázquez-Suárez,Marta Martínez-Valle,Marta Nonide,Mónica Pozo-López,Pablo Bernardo-Alba,Pablo Galván-Núñez,Polácido J. Martínez-Pérez,Rafael Castro,Raquel Suárez-Coto,Raquel Suárez-Noriega,Rocío Guinea,Rosa B. Quintana,Sara de Cima,Segundo A. Hedrera,Sonia I. Laca,Susana Llorente-Álvarez,Susana Pascual,Teodorna Cimas,Anthony Mathur,Eleanor McFarlane-Henry,Gerry Leonard,Jessry Veerapen,Mark Westwood,Martina Colicchia,Mary Prossora,Mervyn Andiapen,Saidi A Mohiddin,Valentina Lenzi,Jun Chong,Rohin Francis,Amy Pine,Caroline Jamieson-Leadbitter,Debbie Neal,J. Din,Jane McLeod,Josh Roberts,Karin Polokova,Kristel Longman,Lucy Penney,Nicki Lakeman,Nicki Wells,Oliver Hopper,Paul Coward,Peter O'Kane,Ruth Harkins,Samantha Guyatt,Sarah Kennard,Sarah Orr,Stephanie Horler,Steve Morris,Tom Walvin,Tom Snow,Michael Cunnington,Amanda Burd,Anne Gowing,Arvindra Krishnamurthy,Charlotte Harland,Derek Norfolk,Donna Johnstone,Hannah Newman,Helen Reed,James O'Neill,John P Greenwood,Josephine Cuxton,Julie Corrigan,Kathryn Somers,Michelle Anderson,Natalie Burtonwood,Petra Bijsterveld,Richard Brogan,Tony Ryan,Vivek Kodoth,Arif Anis Khan,Deepti Sebastian,Diana Gorog,Georgina Boyle,Lucy Shepherd,Mahmood Hamid,Mohamed Farag,Nicholas Spinthakis,Paulina Waitrak,Phillipa De Sousa,Rishma Bhatti,Victoria Oliver,Siobhan Walshe,Toral Odedra,Ying X Gue,Rahim Kanji,Alisdair Ryding,Amanda Ratcliffe,Angela Merrick,Carol Horwood,Charlotte Sarti,Clint Maart,Donna Moore,Francesca Dockerty,Karen Baucutt,Louise Pitcher,Mary Ilsley,Millie Clarke,Rachel Germon,Sara Gomes,Thomas Clare,Sunil Nair,Jocasta Staines,Susan Nicholson,Oliver Watkinson,Ian Gallagher,Faye Nelthorpe,Janine Musselwhite,Konrad Grosser,Leah Stimson,Michelle Eaton,Richard Heppell,Sharon Turney,Victoria Horner,Natasha Schumacher,Angela Moon,Paula Mota,Joshua O'Donnell,Abeesh Sadasiva Panicker,Anntoniette Musa,Luke Tapp,Suresh Krishnamoorthy,Valerie Ansell,Danish Ali,Samantha Hyndman,Prithwish Banerjee,Martin Been,Ailie Mackenzie,Andrew McGregor,David Hildick-Smith,Felicity Champney,Fiona Ingoldby,Kirstie Keate,Lorraine Bennett,Nicola Skipper,Sally Gregory,Scott Harfield,Alexandra Mudd,Christopher Wragg,David Barmby,Ever Grech,Ian Hall,Janet Middle,Joann Barker,Joyce Fofie,Julian Gunn,Kay Housley,Laura Cockayne,Louise Weatherlley,Nana Theodorou,Nigel Wheeldon,Pene Fati,Robert F. Storey,James Richardson,Javid Iqbal,Zul Adam,Sarah Brett,Michael Agyemang,Cecilia Tawiah,Kai Hogrefe,Prashanth Raju,Christine Braybrook,Jay Gracey,Molly Waldron,Rachael Holloway,Senem Burunsuzoglu,Sian Sidgwick,Simon Hetherington,Charmaine Beirnes,Olga Fernandez,Nicoleta Lazar,Abigail Knighton,Amrit Rai,Amy Hoare,Jonathan Breeze,Katherine Martin,Michelle Andrews,Sheetal Patale,Amy Bennett,Andrew Smallwood,Elizabeth Radford,James Cotton,Joe Martins,Lauren Wallace,Sarah Milgate,Shahzad Munir,Stella Metherell,Victoria Cottam,Ian Massey,Jane Copestick,Jane Delaney,Jill Wain,Kully Sandhu,Lisa Emery,Charlotte Hall,Chiara Bucciarelli-Ducci,Rissa Besana,Jodie Hussein,Sheila Bell,Abby Gill,Emily Bales,Gary Polwarth,Clare L. East,Ian E. Smith,Joana Oliveira,Saji Victor,Sarah Woods,Stephen P. Hoole,Angelo Ramos,Annaliza Sevillano,Anne Nicholson,Ashley Solieri,Emily Redman,Jean Byrne,Joan Joyce,Joanne Riches,John Davies,Kezia Allen,Louie Saclot,Madelaine Ocampo,Mark Vertue,Natasha Christmas,Raiji Koothoor,Reto Gamma,Wilson Alvares,Stacey Pepper,Barbara Kobson,Christy Reeve,Iqbal S. Malik,Emma Chester,Heidi Saunders,Idah Mojela,Joanna Smee,Justin E. Davies,Nina Davies,Piers Clifford,Priyanthi Dias,Ramandeep Kaur,Silvia Moreira,Yousif Ahmad,Lucy Tomlinson,Clare Pengelley,Amanda Bidle,Sharon Spence,Rasha Al-Lamee,Urmila Phuyal,Hakam Abbass,Tuhina Bose,Rebecca Elliott,Aboo Foundun,Alan Chung,Beth Freestone,Kaeng Lee,Mohamed Elshiekh,George Pulikal,Gurbir Bhatre,James Douglas,Lee Kaeng,Michael Pitt,Richard Watkins,Simrat Gill,Amy Hartley,Andrew J. Lucking,Berni Moreby,Damaris Darby,Ellie Corps,Georgina Parsons,Gianluigi De Mance,Gregor Fahrai,Jenny Turner,Jeremy P. Langrish,Lisa Gaughran,Mathias Wolyrum,Mohammed Azkhalil,Rachel Bates,Rachel Given,Rajesh K Kharbanda,Rebecca Douthwaite,Steph Lloyd,Stephen Neubauer,Deborah Barker,Anne Suttling,Charlotte Turner,C Smith,Colin Longbottom,David Ross,Denise Cunliffe,Emily Cox,Helena Whitehead,Karen Hudson,Leslie Jones,Martin Drew,Nicholas Chant,Peter Haworth,Robert Capel,Rosalynn Austin,Serena Howe,Trevor Smith,Alex Hobson,Philip Strike,Huw Griffiths,Brijesh Anantharam,Pearse Jack,Emma Thornton,Adrian Hodgson,Alan Jennison,Anna McSkeane,Bethany Smith,Caroline Shaw,Chris Leathers,Elissa Armstrong,Gayle Carruthers,Holly Simpson,Jan Smith,Jeremy Hodierne,Julie Kelly,Justin Barclay,Kerry Scott,Lisa Gregson,Louise Buchanan,Louise McCormick,Nicci Kelsall,Rachel Mcarthy,Rebecca Taylor,Rebecca Thompson,Rhidian Shelton,Roger Moore,Sharon Tomlinson,Sunil Thambi,Theresa Cooper,Trevor Oakes,Zakhira Deen,Chris Relph,Scott prentice,Lorna Hall,Angela Dillon,Deborah Meadows,Emma Frank,Helene Markham-Jones,Isobel Thomas,Joanne Gale,Joanne Denman,John O'Connor,Julia Hindle,Karen Jackson-Lawrence,Karen Warner,Kelvin H. Lee,Robert Upton,Ruth Elston,Sandra Lee,Vinod Venugopal,Amanda Finch,Catherine Fleming,Charlene Whiteside,Chris Pemberton,Conor Wilkinson,Deepa Sebastian,Ella Riedel,Gaia Giuffrida,Gillian Burnett,Helen Spickett,James Glen,Janette Brown,Lauren Thornborough,Lauren Pedley,Maureen Morgan,Natalia Waddington,Oliver Brennan,Rebecca Brady,Stephen Preston,Chris Loder,Ionela Vlad,Julia Laurence,Angelique Smit,Kirsty Dimond,Michelle Hayes,Loveth Paddy,Jacolene Crause,Nadifa Amed,Priya Kaur-Babooa,Roby Rakhit,Tushar Kotecha,Hossam Fayed,Antonis N. Pavlidis,Bernard Prendergast,Brian Clapp,Divaka Perara,Emma Atkinson,Howard Ellis,Karen Wilson,Kirsty Gibson,Megan Smith,Muhammed Zeeshan Khawaja,Ruth Sanchez-Vidal,Simon Redwood,Sophie Jones,Aoife Tipping,Anu Mary Oommen,Cara Hendry,Fazin Fath-Orboubadi,Hannah Phillips,Laurel Kolakaluri,Martin Sherwood,Sarah Mackie,Shilpa Aleti,Thabitha Charles,Liby Roy,Robert A. Henderson,Rod Stables,Michael S. Marber,Alan Berry,Andrew N. Redington,Kristian Thygesen,Henning Rud Andersen,Colin Berry,Andrew Copas,T W Meade,Henning Kelbæk,Héctor Bueno,Paul von Weitzel-Mudersbach,Grethe Andersen,Andrew Ludman,Nicholas L. Cruden,Dragan Topic,Zlatko Mehmedbegovic,Jesus Maria de la Hera Galarza,Steven Robertson,Laura Van Dyck,Rebecca Chu,Josenir Astarci,Zahra Jamal,Daniel Hetherington,Lucy Collier +581 more
TL;DR: Remote ischaemic conditioning does not improve clinical outcomes at 12 months in patients with STEMI undergoing PPCI, and the primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 years in the intention-to-treat population.