Emma L. Taylor

TL;DR: It is important to realize that oxidative stress is a nuanced phenomenon that is difficult to characterize, and one biomarker is not necessarily better than others, and the vast diversity in oxidative stress between diseases and conditions has to be taken into account when selecting the most appropriate biomarker.

TL;DR: The concept that ROS/RNS-mediated protein damage creates neoepitopes, resulting in autoantibody formation against proteins, e.g. type-II collagen and the complement component, C1q, have been detected in inflammatory autoimmune diseases are highlighted.

TL;DR: The improved method revealed a significant association of AOPP levels with age, and a possible link between plasma oxidising capacity and endothelial and/or vascular dysfunction, in EDTA-anticoagulated plasma samples from 52 patients with diabetes and 38 nondiabetic control subjects.

TL;DR: The development, validation and clinical application of a novel electrochemiluminescence‐based ELISA for nitrotyrosine which provides superior sensitivity and may be applicable as a means to determine oxidative stress in primary and cultured cell populations is reported.

TL;DR: The application of oxidative stress-associated measures to BD blood samples offered no supplemental diagnostic or disease activity information to that provided by standard laboratory measures of inflammation, and S-nitrosothiols and 3-nitrotyrosine appeared not to be markers for active BD.