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Annie R. Knight
Researcher at University of Exeter
Publications - 5
Citations - 788
Annie R. Knight is an academic researcher from University of Exeter. The author has contributed to research in topics: Superoxide dismutase & Oxidative stress. The author has an hindex of 4, co-authored 5 publications receiving 525 citations.
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Journal ArticleDOI
Clinical Relevance of Biomarkers of Oxidative Stress
Jeroen Frijhoff,Paul G. Winyard,Neven Zarkovic,Sean S. Davies,Roland Stocker,David Cheng,Annie R. Knight,Emma L. Taylor,Jeannette Oettrich,Tatjana Ruskovska,Ana Čipak Gašparović,Antonio Cuadrado,Daniela Weber,Henrik E. Poulsen,Tilman Grune,Harald H.H.W. Schmidt,Pietro Ghezzi +16 more
TL;DR: It is important to realize that oxidative stress is a nuanced phenomenon that is difficult to characterize, and one biomarker is not necessarily better than others, and the vast diversity in oxidative stress between diseases and conditions has to be taken into account when selecting the most appropriate biomarker.
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Oxidative stress in autoimmune rheumatic diseases
Miranda J. Smallwood,Ahuva Nissim,Annie R. Knight,Matthew Whiteman,Richard C Haigh,Paul G. Winyard +5 more
TL;DR: Measurement of autoantibodies against oxidatively modified antigens may be diagnostic of specific autoimmune diseases, including anti‐carbamylated proteins and anti‐oxidized type II collagen antibodies.
Journal ArticleDOI
A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.
Annie R. Knight,Emma L. Taylor,Roman A. Lukaszewski,Karina Tveen Jensen,Eleri Jones Helen,Jane E. Carré,Michail N. Isupov,Jennifer A. Littlechild,Stephen J. Bailey,Emily Brewer,Timothy J. McDonald,Andrew R. Pitt,Corinne M. Spickett,Paul G. Winyard +13 more
TL;DR: The development, validation and clinical application of a novel electrochemiluminescence‐based ELISA for nitrotyrosine which provides superior sensitivity and may be applicable as a means to determine oxidative stress in primary and cultured cell populations is reported.
Journal ArticleDOI
Factors associated with depression in people with inflammatory bowel disease: The relationship between active disease and biases in neurocognitive processing.
Ben Wilkinson,Leanne Trick,Annie R. Knight,Vincent Valton,James R Goodhand,Nicholas A. Kennedy,Neel Heerasing,Tariq Ahmad,Amy R. Bland,Rebecca Elliott,Jonathan P. Roiser,Chris Dickens +11 more
TL;DR: The role of emotional processing biases in contributing to depression among people with IBD is investigated in a cross‐sectional study.
Journal ArticleDOI
Mortality in patients hospitalised with Crohn’s disease: authors’ reply
Nicholas A. Kennedy,J. Bauer,D. N. Clark,A. M. Crowe,Annie R. Knight,James Farley Nicholls,Jack Satsangi +6 more
TL;DR: A nationwide linkage analysis in Scotland to assess mortality following hospital admission for Crohn’s disease and patterns of hospitalizations to centers with high volume of admissions for inflammatory bowel disease and their impact on mortality are presented.