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Enkhtuya Radnaa
Researcher at University of Texas Medical Branch
Publications - 25
Citations - 242
Enkhtuya Radnaa is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Medicine & Microvesicles. The author has an hindex of 4, co-authored 13 publications receiving 47 citations.
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Journal ArticleDOI
Extracellular vesicle mediated feto-maternal HMGB1 signaling induces preterm birth
Enkhtuya Radnaa,Lauren S. Richardson,Lauren S. Richardson,Samantha Sheller-Miller,Tuvshintugs Baljinnyam,Mariana de Castro Silva,Ananth K. Kammala,Rheanna Urrabaz-Garza,Talar Kechichian,Sungjin Kim,Arum Han,Ramkumar Menon +11 more
TL;DR: It is determined that fetal exosome mediated paracrine signaling can generate inflammation and induce parturition and in vivo functional validation of FMi-OOC experiments strengthens the reliability of such devices to test physiologic and pathologic systems.
Journal ArticleDOI
Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models.
Samantha Sheller-Miller,Enkhtuya Radnaa,Jae-Kwang Yoo,Eun Soo Kim,Kyungsun Choi,Young Eun Kim,Yu-na Kim,Lauren Richardson,Chulhee Choi,Ramkumar Menon +9 more
TL;DR: In this article, extracellular vesicles (exosomes) were engineered to contain an NF-κB inhibitor, termed super-repressor (SR) IκBα.
Journal ArticleDOI
Oxidative stress-induced downregulation of glycogen synthase kinase 3 beta in fetal membranes promotes cellular senescence†.
Narmada Lavu,Lauren Richardson,Enkhtuya Radnaa,Talar Kechichian,Rheanna Urrabaz-Garza,Samantha Sheller-Miller,Elizabeth A. Bonney,Ramkumar Menon +7 more
TL;DR: OS causes activation of p38MAPK that can inactivate GSK3?
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Microvesicles and exosomes released by amnion epithelial cells under oxidative stress cause inflammatory changes in uterine cells
Hend I. Shahin,Enkhtuya Radnaa,Ourlad Alzeus G. Tantengco,Ourlad Alzeus G. Tantengco,Talar Kechichian,Ananth K. Kammala,Samantha Sheller-Miller,Brandie D. Taylor,Ramkumar Menon +8 more
TL;DR: It is hypothesized that fetal cells-derived exosomes and microvesicles under oxidative stress carry unique cargo and traffic through feto-maternal interface, which cause inflammation in uterine cells associated with parturition.
Journal ArticleDOI
Environmental pollutant induced cellular injury is reflected in exosomes from placental explants.
Samantha Sheller-Miller,Enkhtuya Radnaa,Yuko Arita,Darios Getahun,Richard J. Jones,Morgan R. Peltier,Ramkumar Menon +6 more
TL;DR: Environmental exposure of placental explants did not change the quantity of exosomes or their characteristics, however, exosome cargo composition exposed to some environment pollutants may be involved in placental nuclear and cellular injury and inflammation.