Ennio Tasciotti

TL;DR: In an attempt to better understand the interactions between nanocarriers and biological systems, the plasma proteins adsorbed on the surface of multicomponent liposomes were analyzed and the physical properties and ultrastructure of liposome/PC complexes and the aggregation process that occurs whenliposomes are dispersed in plasma were analyzed.

TL;DR: This biomimetic model mimics the evolution of tumors with different grade of aggressiveness fostered by a hypoxic niche and provides a relevant technology to dissect the events involved in cancer progression.

TL;DR: A simple and versatile method to transiently overexpress the hyaluronic acid (HA) receptor, CD44, on MSC membranes, to improve their homing potential towards an inflammatory site without affecting their behavior is reported.

TL;DR: The use of leukosomes is reported to target and deliver doxorubicin, a model chemotherapeutic, to tumors in syngeneic murine models of breast cancer and melanoma models, demonstrating the promise of using biomimetic nanovesicles for effective cancer management in solid tumors.

TL;DR: It is reported that fusion of TK to an 11-amino-acid peptide from the basic domain of the HIV-1 Tat protein (Tat11) imparts cell membrane translocating ability to the enzyme and significantly increases its cytotoxic efficacy.