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Ennio Tasciotti
Researcher at Houston Methodist Hospital
Publications - 216
Citations - 9469
Ennio Tasciotti is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Drug delivery & Tissue engineering. The author has an hindex of 42, co-authored 212 publications receiving 7526 citations. Previous affiliations of Ennio Tasciotti include University of Akron & Open University.
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Journal ArticleDOI
Phosphoprotein-based biomarkers as predictors for cancer therapy.
Angela M. Carter,Chunfeng Tan,Karine Pozo,Rahul Telange,Roberto Molinaro,Roberto Molinaro,Ailan Guo,Enrica De Rosa,Jonathan O. Martinez,Shanrong Zhang,Nilesh Kumar,Masaya Takahashi,Thorsten Wiederhold,Hans K. Ghayee,Sarah C. Oltmann,Karel Pacak,Eugene A. Woltering,Kimmo J. Hatanpaa,Fiemu E. Nwariaku,Elizabeth G. Grubbs,Anthony J. Gill,Bruce G. Robinson,Frank Gillardon,Sushanth Reddy,Renata Jaskula-Sztul,James A. Mobley,M. Shahid Mukhtar,Ennio Tasciotti,Herbert Chen,James A. Bibb +29 more
TL;DR: It is demonstrated that mouse models of neuroendocrine cancer are responsive to selective Cdk5 inhibitors and biomimetic nanoparticles are effective vehicles for enhanced tumor targeting and reduction of drug toxicity.
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Identification of a binding site of the human immunodeficiency virus envelope protein gp120 to neuronal specific tubulin
Valeriya Avdoshina,Francesca Taraballi,Simona Dedoni,Claudia Corbo,Mikell Paige,Yasemin Saygideger Kont,Aykut Üren,Ennio Tasciotti,Italo Mocchetti +8 more
TL;DR: This study discovered novel mechanisms of gp120 neurotoxicity that could explain how the envelope protein promotes neurite pruning and designed a small peptide (Helix‐A) that displaced gp120 from binding to TUBB3, a major component of neuronal microtubules.
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Optimizing cell seeding and retention in a three-dimensional bioengineered cardiac ventricle: The two-stage cellularization model.
TL;DR: The study demonstrates initial effectiveness of the two‐stage cell delivery concept, based on function and biological metrics, and demonstrates the potential to improve cellularization efficiency, and retention.
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Reproducible and Characterized Method for Ponatinib Encapsulation into Biomimetic Lipid Nanoparticles as a Platform for Multi-Tyrosine Kinase-Targeted Therapy
Assaf Zinger,Gherardo Baudo,Tomoyuki Naoi,Federica Giordano,Stefania Lenna,Matteo Massaro,April Ewing,Ha Ram Kim,Ennio Tasciotti,Jason T. Yustein,Francesca Taraballi +10 more
TL;DR: The results indicate that the fabrication method is reproducible, nonuser-dependent, efficient in loading Pon, and applicable toward repurposing numerous therapeutic agents previously shelved due to toxicity profiles.
Journal ArticleDOI
Microfluidic enrichment of small proteins from complex biological mixture on nanoporous silica chip
Ye Tony Hu,Ashwini Gopal,Kevin Lin,Yang Peng,Ennio Tasciotti,Xiaojing John Zhang,Mauro Ferrari +6 more
TL;DR: This letter presents a novel, highly efficient method for the extraction of low-molecular weight (LMW) proteins from biological fluids, represented by a mixture of standard proteins, using integrated microfluidic systems.